Initial experience of 3 tesla apparent diffusion coefficient values in differentiating benign and malignant thyroid nodules.

Purpose: To evaluate the role of diffusion-weighted magnetic resonance imaging (DWMRI) in differentiating benign and malignant thyroid nodules using a 3 Tesla (T) MRI scanner.

Materials And Methods: Twenty-eight nodules in 25 patients and 14 healthy control cases were included in the study. DWMRI was acquired with 6 b values with a 3T MRI scanner.

Initial evaluation of 11C-DPA-713, a novel TSPO PET ligand, in humans.

Unlabelled: Translocator protein (TSPO) is upregulated in activated microglia and thus can serve as a marker of neuroinflammation. Recently, a novel radioligand, (11)C-N,N-diethyl-2-[2-(4-methoxyphenyl)-5,7-dimethyl-pyrazolo[1,5-a]pyrimidin-3-yl]-acetamide ((11)C-DPA-713), has been described that binds to TSPO with high affinity. Here, we report the first examination of (11)C-DPA-713 in human subjects using PET.

Protein-losing enteropathy detected by Tc-99m-MDP abdominal scintigraphy.

This case report describes the incidental finding of intestinal leakage during bone scan imaging with Tc-99m methylene diphosphonate (MDP) in a patient with previously diagnosed protein-losing enteropathy (PLE). Most radiopharmaceuticals reported in the literature that are useful for making this diagnosis are not generally available for clinical use in the United States. This report suggests that Tc-99m-MDP is useful for confirming the diagnosis of PLE although further investigations are indicated to determine the accuracy of this method.

Imaging of musculoskeletal bacterial infections by [124I]FIAU-PET/CT.

Background: Traditional imaging techniques for the localization and monitoring of bacterial infections, although reasonably sensitive, suffer from a lack of specificity. This is particularly true for musculoskeletal infections. Bacteria possess a thymidine kinase (TK) whose substrate specificity is distinct from that of the major human TK.

Advances in imaging of the paranasal sinuses.

Significant changes in surgical technique, surgical instrumentation, and imaging technology have occurred during the past 20 years. These changes have largely resulted from a better understanding of the pathophysiology ofa specific pathologic process, the inflammation of paranasal sinus mucosa. As surgical techniques were adapted to address clinical issues, new instrumentation was developed.