Publications by authors named "Ovidiu F Coza"
Article Synopsis
- Precision medicine in lung cancer research has led to improved patient survival and quality of life, especially through targeted therapies for non-small cell lung cancer (NSCLC) with ALK gene rearrangement.* -
- This review highlights ALK tyrosine kinase inhibitors (TKIs), their mechanisms of action and resistance, various gene detection methods, and future research aimed at overcoming resistance.* -
- Crizotinib was the first approved TKI and while newer drugs like alectinib and brigatinib have been developed, resistance remains a significant challenge with half of the resistance mechanisms still unidentified.*
Ovarian cancer is one of the most common cancers worldwide, and is associated with a prior diagnosis of endometriosis in several cases. Our aim was to correlate genetic and methylation profile of ovarian endometrioid ovarian cancer and endometriosis patients. We evaluated the genetic profile of 50 ovarian endometriosis and 20 ovarian endometrioid carcinoma samples using next generation sequencing technology.
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