[Assessment of the size of the thalamus as a method for the evaluation of the activity of neurodegenerative process after the treatment with cerebrolisin in young patients with multiple sclerosis].

The aim of the study was to describe the atrophy of the thalamus in young patients with active relapsing multiple sclerosis (MS) treated with cerebrolysin. Eighteen MS patients (mean age 20.10±0.

[Neurological manifestations of HIV-infection (review)].

Current data on the etiology, pathogenesis, diagnosis and treatment principles of HIV are reviewed. The special attention is focused on affections of the nervous system (neuro-AIDS). Primary and secondary manifestations of these affections are described.

[The comparative study of efficacy and tolerability of intramuscular introduction of beta-interferon-1a in adults and adolescents with remitting multiple sclerosis].

The experience of the treatment of patients with remitting multiple sclerosis (MS) with intramuscular introduction of beta-interferon-1a (avonex) is presented. Seventeen children and adolescents, aged from 11 to 18 years, and 55 adults, aged over 55 years, were treated for at least one-year period. Results revealed a significant reduction of exacerbations in both groups (from 1.

[Efficacy and tolerability of long-term using of glatimer acetate (copaxone): a 10 year-study in the Moscow Municipal Multiple Sclerosis center].

Experience of 10-year administration of glatimer acetate (copaxone) in 74 patients with active remitting multiple sclerosis is summarized. The significant decrease in the frequency of exacerbations was seen over these ten years. Disease severity on the EDSS was stable and decreased only to the end of the 10-year period.

[Instrumental methods of the rehabilitation of motor disorders in patients with multiple sclerosis].

Motor and coordination disorders are the most prominent clinical presentations of multiple sclerosis. Currently, good results were achieved in the pathogenetic treatment of the disease. However methods of treatment of motor and coordination disorders are not widely used.

[Symptomatic therapy of bladder hyporeflexia in patients with multiple sclerosis].

Symptomatic therapy of bladder hyporeflexia in patients with multiple sclerosis by intermittent catheterization in cases of insufficient efficacy of alpha-adrenoblockers allows to prevent bacterial infection complications and chronic renal failure and to achieve significant improvement of quality of life of such patients.

[The results of longitudinal use of copaxone and betaferon in Moscow Multiple Sclerosis Center: issues of efficacy and adherence to therapy].

In last decades, practical neurologists are able to use DMT in multiple sclerosis (MS) in every day practice. This paper presents data of 3-year study of DMT (copaxone and betaferon) treatment of 280 patients with definite diagnosis of multiple sclerosis (MS), 166 patients regularly receiving DMT (104--copaxone and 62--betaferon) for, at least, 3 years. Clinical symptoms of the patients, reasons of treatment withdrawal (48--copaxone and 31--betaferon) and the features of MS course after the withdrawal are analyzed.

[Quantitative assessment of impact of ambulatory polyclinic service on mortality].

Index, based on official statistic data, revealing regional differences and dynamics of medical care input into death rate is proposed. Its enhancing potential for health programs in ambulatory care is proved.

[Methodology and research of public health].

The statistical sources now available within Russia's healthcare systems as well as their potentialities in respect to evaluating the public health standards are analyzed in the paper both analytically and comparatively. The most informative sources are enumerated; additionally to the verified data of the medical-and-demographic nature, parameters of the integrated health condition, which are based on questionnaires, self-assessment and medical documentation known to respondents, are suggested. The above methods and evaluation tools, that are in line with the world standards, ensure the compatibility of data and provide for a more tense usage of joint healthcare programs.

[Sources and evaluation of study methods in public health research].

The statistical sources available in Russia's healthcare and the potentialities of such sources for evaluating the general level of the population health were comparatively analyzed. The most informative sources were defined; additionally to the stable data of the medical-and-demographic nature and with due respect to the data of medical documents known by respondents integrated parameters of health were suggested, which are based on questionnaires and self-evaluation of health. The above methods of health investigation and evaluation accepted in the world practice ensure the comparability of data and a more active cooperation within joint healthcare projects.

[Secondary stroke prophylaxis: the advantages of care in neurological center for specialized outpatient treatment].

In neurological center for specialized course outpatient treatment, a higher level of medical care, comparing to general clinics, is provided for post- stroke patients. The continuous antiaggregants intake and modern antihypertensive therapy allowed to reduce significantly a frequency of secondary stroke in comparison to standard care for such patients in general outpatient clinics (4.6% versus 24% during a year; p < 0.

[Methodological and organizational approaches to the development of socio-hygienic monitoring of the health status of the population].

Sociohygienic monitoring is regarded as a tool of active observation and justified intervention to correct health formation by means of a number of specific components of the monitoring system. It is suggested that the capacities of some monitoring components sufficient for a research and experimental base to promote health, be extensively introduced into practice of the public health system. Emphasis is laid on an important role of the elaboration of sociopsychological measures to work with some groups of the population and their informed consent for collaboration while implementing the preventive programs of the public health system.

[Secondary prevention of stroke: advantages of work under the conditions of a neurological center using specialized course ambulatory treatment].

A neurologic center of specialized course outpatient treatment provides a higher level of medical service to patients with prior stroke as compared to general outpatient treatment. A continuous use of antiaggregants and currently available antihypertensive agents caused a considerable decrease in the incidence of recurrent stroke as compared to the conventional treatment of such patients in the outpatient setting (4.6% versus 24% during the year, p < 0.