Publications by authors named "Ouxi Wang"
Clinical identification and microbiota analysis of and pneumonia by metagenomic next-generation sequencing.
Front Cell Infect Microbiol
July 2023
Article Synopsis
- Chlamydial pneumonia is increasingly being caused by rare pathogens, often leading to misdiagnosis and delayed treatments due to non-specific symptoms and traditional detection limitations.
- The study utilized metagenomic next-generation sequencing (mNGS) to analyze the pathogen profiles and lower respiratory tract microbiota of pneumonia patients with varying chlamydial infections.
- Results showed that patients infected with one specific pathogen had more co-infections and lower microbiota diversity, indicating that chlamydial infections significantly influence lung microbiota and potentially worsen clinical outcomes.
Background: Early diagnosis of colorectal cancer could significantly improve the prognosis and reduce mortality. However, indeterminate diagnosis is often met in pathology diagnosis in biopsy samples. Abnormal expression of long non-coding RNA (lncRNA) is associated with the initiation and progression of colorectal cancer.
View Article and Find Full Text PDFAccurate diagnosis of the origin of brain metastases (BMs) is crucial for tailoring an effective therapy to improve patients' prognosis. BMs of unknown origin account for approximately 2-14% of patients with BMs. Hence, the aim of this study was to identify the original cancer type of BMs based on their DNA methylation profiles.
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