Object: Osteogenesis imperfecta (OI), which usually results from mutations in type I collagen genes, causes bone fragility and deformities. The head is often abnormally shaped, and changes in skull base anatomy in the form of basilar impression and basilar invagination have been reported. The authors analyzed the skull base anatomy on standardized lateral cephalograms from 54 patients with OI (Types I, III, and IV) and 108 control volunteers.
View Article and Find Full Text PDFOsteogenesis imperfecta (OI) is a heterogeneous group of connective tissue diseases that mainly manifest as bone fragility and skeletal deformity. In most families it segregates as a dominant trait and results from mutations in type I collagen genes. In this study we analyzed the size and form of the bony structures in heads of 59 consecutive patients with OI types I, III, or IV (Sillence classification), using lateral radiographs.
View Article and Find Full Text PDFEnviron Health Perspect
September 2004
Children's developing teeth may be sensitive to environmental dioxins, and in animal studies developing teeth are one of the most sensitive targets of toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Twenty-five years after the dioxin accident in Seveso, Italy, 48 subjects from the contaminated areas (zones A and B) and in patches lightly contaminated (zone R) were recruited for the examination of dental and oral aberrations. Subjects were randomly invited from those exposed in their childhood and for whom frozen serum samples were available.
View Article and Find Full Text PDFThe purpose of this population-based cohort was to measure maximal bite force (MBF) in the molar and incisal regions and to examine whether MBF was associated with TMD, gender, occlusion (in terms of overjet, overbite, and total number of occluding contacts), and body mass index (BMI). MBF in the molar and incisal regions was measured using a calibrated method in 384 (196 males, 188 females) and 357 (181 males, 176 females) subjects, respectively. Two attempts in each region (right molar, left molar, and incisal) were made in random order.
View Article and Find Full Text PDFThe aim of the present study was to detect possible associations between trunk and cervical asymmetry and facial symmetry. Frontal cephalograms prepared in the natural head position, representing 79 subjects (40 males, 39 females) with mild to moderate trunk asymmetry, were analyzed separately for thoracic humps, lumbar prominences, and cervical inclination by discriminating two groups: right-sided-dominant and left-sided-dominant. The differences between the groups were analyzed using an unpaired 2-group t test.
View Article and Find Full Text PDFMaximal bite force (MBF) and its associations with craniofacial morphology and spinal posture were studied in a group of young adults (46 M and 38 F) aged 21 to 23 years. MBF was recorded in molar and incisal regions. Sagittal spinal posture was measured by spinal pantography and trunk asymmetry at thoracic and lumbar levels by a forward-bending test.
View Article and Find Full Text PDFAims: To investigate whether involvement of the temporomandibular joint (TMJ) can occur in men with Reiter's disease (RD).
Methods: Forty-nine men with RD and 49 individually matched (gender, age and dentition type) controls with no known general joint disease were screened for findings in the TMJ by panoramic tomography.
Results: Duration of subjective symptoms (e.