Purpose: To investigate the clinical outcome of closed radial wedge osteotomy (CRWO) for Preiser's disease.
Methods: CRWO was performed for four patients with Preiser's disease between 2000 and 2005. All patients were diagnosed by X-ray and magnetic resonance imaging (MRI) scans.
Avascular necrosis involving more than one carpal bone is rare, and the appropriate treatment for this condition has not yet been established. In this report, two patients with concomitant Preiser's and Kienböck's disease who also had severe wrist pain without obvious traumas were treated by closing radial wedge osteotomy (CRWO). Clinical evaluation showed that CRWO was effective against both conditions and indicated that it is more suitable for early stage than stage II diseases of the Hebert and Lichtman classifications.
View Article and Find Full Text PDFMesenchymal stem cells (MSCs) reside in many types of tissue and are able to differentiate into various functional cells including osteoblasts. Recently, adipose tissue-derived MSCs (AMSCs) have been shown to differentiate into many lineages, and they are considered a source for tissue regeneration. The purpose of this study was to compare the osteogenic differentiation capability of MSCs from bone marrow (BMSCs), MSCs from periosteum (PMSCs), and AMSCs using in vitro culture and in vivo implantation experiments.
View Article and Find Full Text PDFA case of Preiser's disease treated with closing radial wedge osteotomy is reviewed and the therapeutic effect is reported. A good result was obtained in the short term and we believe that this surgical method could become one of the choices for surgical treatment to alleviate pain in Preiser's disease.
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