Publications by authors named "Oura S"

A 61-year-old woman underwent an emergent operation with sigmoid colon cancer resection, colostomy, and ileostomy on colon perforation. The low ileostoma, caused by intra-abdominal bad conditions, had irritated the surrounding skin after surgery, intermittently forcing the patient to fast for a certain period. Six months after the operation, under the judgment that re-ileostomy, essential for hospital discharge, seemed very difficult through another laparotomy, we attempted to make the ileostoma higher not with pulling the ileum from the abdomen but with lowering the surrounding skin using skin flap formation techniques.

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Intraoperative hyperkalemia is particularly common in patients with chronic kidney disease (CKD). We report two cases of intraoperative hyperkalemia occurring under general anesthesia, while potassium levels remained stable with regional anesthesia alone. Case 1 involved a 69-year-old male with CKD who underwent total thyroidectomy under general anesthesia and developed intraoperative hyperkalemia, requiring glucose-insulin (GI) therapy.

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Background: Inhibition of sperm maturation in the epididymis is a promising post-testicular strategy for short-acting male contraceptives. It has been shown that ROS1, a receptor tyrosine kinase expressed in the epididymis, is essential for epididymal differentiation, sperm maturation, and male fertility in mice. However, it is unknown if inhibition of ROS1 suppresses male fertility reversibly.

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Article Synopsis
  • A 58-year-old woman with a stomach lesion underwent tests revealing a lobulated mass, leading to a fine needle biopsy that suggested an inflammatory fibroid polyp.
  • The patient had laparoscopic surgery, and the postoperative analysis identified the lesion as a gastric hamartomatous inverted polyp (GHIP) due to its specific growth patterns and tissue characteristics.
  • The study emphasizes the importance of distinguishing between fibrous tumors and GHIPs based on ultrasound echo patterns, which can aid in accurate diagnosis.
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Introduction: Nipple retraction has long been regarded as an absolute contraindication factor for nipple preservation in breast cancer surgery.

Case Presentation: A 62-year-old woman was referred to our hospital for the treatment of breast cancer with slight nipple retraction. Imaging findings showed neither direct cancer infiltration to the nipple-areolar complex nor lymphadenopathy.

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A 66-year-old woman with metastatic mucinous breast cancer was referred to our hospital. The patient had lymph node and multiple lung metastases judged as progressive disease. Positron emission tomography showed radio tracer uptake neither in the axillary lymph nodes nor in the lung metastases.

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Article Synopsis
  • * Despite the lung nodule's rapid growth, a PET scan indicated a low maximum standardized uptake value (SUV max), which is unusual for metastatic tumors.
  • * Post-surgery analysis revealed the lung tumor contained atypical cells with clear cytoplasm and lipid droplets, suggesting that the low SUV max in CCRCC metastases might be due to the tumor's lipids and glycogen content.
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No studies have reported breast cancer cases developed in the chronic expanding hematoma (CEH). Case presentation: A 47-year-old woman was referred to our hospital for the treatment of a large breast mass. Ultrasound showed that the tumor had an intra-cystic tumor pattern.

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Article Synopsis
  • * A major challenge identified is the poor adhesion of human pluripotent stem cells (PSCs) to animal PSCs, which hinders the creation of effective chimeras.
  • * To address this, researchers developed a synthetic biology technique that uses nanobody-antigen pairs to boost cell adhesion, leading to better integration of human PSCs in mouse embryos and improving understanding of cell interactions during early development.
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Introduction: Apocrine adenoma of the breast is extremely rare and its typical images remain uncertain.

Case Presentation: A 66-year-old woman was incidentally found of her left breast tumor with computed tomography for ascending colon cancer staging work. Mammography showed a well-demarcated oval mass.

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Background: Due to its indolent biology and high estrogen receptor positivity of mucinous breast cancer, vast majority of locally advanced mucinous breast cancer (LABC) are treated with first-line endocrine therapy.

Case Presentation: A 50-year-old woman was referred to our hospital for the treatment of her huge breast tumor. Computed tomography showed an oval solid tumor, 17 cm in size, and lymph node swelling in both the axilla and parasternum.

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A 62-year-old woman showed an elevation of carcinoembryonic antigen (CEA) level 15 years after the left breast cancer, i.e., tubule forming type luminal micro invasive cancer, operation.

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Article Synopsis
  • The sperm flagellar axoneme structure is crucial for sperm motility and is highly conserved across different species, aiding in fertilization.
  • Mycbpap is primarily expressed in mouse and human testes and is vital for male fertility; its absence disrupts docking between the centrosome and nuclear envelope, causing defects in flagellar development.
  • Research on transgenic mice showed that restoring MYCBPAP can recover fertility, and further studies revealed key protein interactions that highlight MYCBPAP’s role in regulating sperm tail formation and centrosome functions.
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This study evaluated the reliability and validity of the Japanese version of the Body Talk Scale (BTS), designed to measure negative fat talk, negative muscle talk, and positive body talk. The study also explored the longitudinal associations between each body talk category and body dissatisfaction. We conducted two separate studies among university students in Japan.

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A 44-year-old woman was referred to our hospital for the examination and treatment of a presumed gallbladder tumor. Both ultrasound and computed tomography showed an intracystic tumor but failed to point out the discontinuity between the cystic lesion and the gallbladder. Magnetic resonance imaging, however, could clearly depict the presumed intracystic tumor and the discontinuity between the gallbladder and the target lesion.

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A 10-year-old girl was admitted to our hospital due to acute pancreatitis. Computed tomography showed an intra-gastric mass containing multiple small air bubbles. Ultrasound showed a well-circumscribed large oval mass with a broad acoustic shadow.

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A 73-year-old woman was pointed out of her right breast tumor on screening computed tomography (CT). Mammography showed distortion of the mammary gland and skin retraction. Ultrasound (US) showed an irregular tumor with hyperechoic haloes adjacent to the anterior tumor borders.

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A 69-year-old woman with chronic hepatitis C virus (HCV) infection was referred to our hospital due to liver enzyme abnormalities. Four years after anti-HCV therapy, the patient with sustained virologic response and no clinical symptoms developed an oval hepatic mass with mixed high and low internal echoes near the portal vein on ultrasound. Magnetic resonance imaging (MRI) of the liver lesion showed a slightly hypo intense pattern on T1-weighted images, a hyper intense pattern both on T2- and diffusion-weighted images, a slight rim enhancement pattern with no intra-lesional enhancement up to the late phase, and a very low intense pattern on hepatobiliary phase images.

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Remimazolam is a newly developed ultra-short-acting benzodiazepine that exerts sedative effects. This study aimed to clarify the effects of remimazolam on cardiac contractility. In a randomised-parallel group trial, haemodynamic parameters were compared between propofol (n = 11) and remimazolam (n = 12) groups during the induction of general anaesthesia in patients undergoing non-cardiac surgery.

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Article Synopsis
  • * A study used CRISPR/Cas9 to create knockout mouse models to investigate the importance of Pate family genes and related protein-coding genes in male fertility.
  • * Results revealed that male mice lacking certain combinations of these genes showed reduced fertility due to lower levels of a key protein, ADAM3, and issues with sperm migration, indicating the collaborative function of these genes in promoting fertility.
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A 56-year-old woman was referred to our hospital due to dry mouth. Diagnostic upper gastrointestinal endoscopy showed slightly elevated lesions both on the anterior wall and lesser curvature in the upper part of the stomach. Biopsy-proven tuble-forming atypical cells in the two lesions led us to treat the presumed early gastric cancers with endoscopic submucosal dissection (ESD).

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A 67-year-old man with abdominal pain and vomiting was referred to our hospital for the treatment of ileus. Enhanced computed tomography (CT) showed marked dilatation of the ileum and a presumed cecal tumor. After the intestinal decompression using nasogastric tube, a colonoscopy showed a type 3 tumor in the cecum.

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A 71-year-old man with slight fever and dull abdominal pain was referred to our hospital. He had been receiving methotrexate (MTX) to treat his rheumatoid arthritis for more than 6 years but stopped taking MTX after admission due to the rapid aggravation of his liver function. Computed tomography (CT) showed multiple liver lesions with late enhancement, highly suggesting them to be cholangiocarcinomas.

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A 54-year-old woman with a left breast mass was referred to our hospital. Mammography showed a mass, 2.1cm in size, with micro-lobulated boarders.

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