Co-expression and impact of prostate specific membrane antigen and prostate specific antigen in prostatic pathologies.

Background: The present study was undertaken to relate the co-expression of prostate-associated antigens, PSMA and PSA, with the degree of vascularization in normal and pathologic (hyperplasia and cancer) prostate tissues to elucidate their possible role in tumor progression.

Methods: The study was carried out in 6 normal, 44 benign prostatic hyperplastic and 39 cancerous human prostates. Immunohistochemical analysis were performed using the monoclonal antibody CD34 to determine the angiogenic activity, and the monoclonal antibodies 3E6 and ER-PR8 to assess PSMA and PSA expression, respectively.

[Effect of hexachlorobenzene on some male reproductive parameters in Meriones unguiculatus].

Organochlorine pesticides are known to cause disturbances in many physiological functions. The effects of in vivo administered hexachlorobenzene (HCB) on the male testicular function were studied in Meriones unguiculatus. Three groups of sexually mature meriones were orally exposed to 1.

[Toxicity of hexachlorobenzene in Meriones unguiculatus: effects on thyroid and liver].

The effect of in vivo administered hexachlorobenzene (HCB) on liver and thyroid was studied on Meriones unguiculatus. HCB (1.6, 4, and 16 mg/kg of body weight) has been administered orally to meriones for 30 days.

[Extrapulmonary tuberculosis in Tunisia. Report of 830 cases. Experience of the Anatomic Pathology Laboratory of the Rabta Hospital].

We present the experience of pathological laboratory of la Rabta hospital in extra-pulmonary tuberculosis. We report an epidemiologic retrospective study of 830 cases occurring in our service over a period of 10 years from 1991 to 2000 and diagnosed by histopathological examination. Various epidemiological, clinical, pathological and diagnostic aspects are discussed.

[Endometrioid carcinoma of the Fallopian tube arising in tubo-ovarian endometriosis. A case report].

The primitive endometrioid carcinoma of the fallopian tube is exceptional. Only three cases have been reported in the literature. Its rise on tubal endometriosis like for the ovary needs to meet the strict histological criteria established by Sampson and Scott in 1953.

[Linguinal metastasis from clear cell carcinoma of the kidney].

Clear cell carcinoma is the most frequent cancer of the kidney (60-80% of cases). This tumour has a great propensity to metastasis. Metastasis lesions appear 15 to 20 years after nephrectomy and differential diagnosis with can be difficult to establish.

[Actinomycosis: report of 21 cases. Experience of the Anatomy and Cytopathologic Pathology Laboratory of the Rabta Hospital].

Actinomycosis is a chronic suppurative granulomatous disease caused by an anaerobic Gram positive germ, Actinomyces. From 1994 to 1999, 21 cases of actinomycosis have been diagnosed in our laboratory. The main localisations were cervicofacial and gynecologic the diagnosis relies on histopathologic examination that shows actinomycosic granules.

[Fibrous inflammatory polyp of the digestive tract. Apropos of 5 cases].

Inflammatory fibroid polyp is a rare benign tumor of the digestive tract. The authors report three cases: two intestinal and one gastric. These cases are of particular interest because of the association ill one case of an intestinal submucosal lipoma with the inflammatory fibroid polyp, and the existence in the gastric case of an inflammatory reaction caused by food debris.

[Collagenous enterocolitis. Apropos of a case and review of the literature].

Collagenous enterocolitis is a recent entity of which only two cases have been published. The authors report the association of collagenous colitis and collagenous sprue in a 67-year-old woman. The diagnosis of collagenous enterocolitis is based on the presence of a duodenal collagen deposit with partial villous atrophy associated with collagenous colitis.

[Abdominal actinomycosis: a rare complication of gastric surgery? Apropos of a case].

One case of abdominal actinomycosis is reported which was detected in a diabetic patient three years after surgery for duodenal peptic ulcer. Gastric actinomycosis is very rare and is usually discovered during surgery for gastric mass. The role of surgery as a predisposing condition to infection is discussed.

[Scleroma of the upper respiratory tract. Apropos of a case of laryngeal localization].

A case of rhinoscleroma with laryngeal localization is reported. Geographic distribution of this granulomatous disease is discussed. Clinical and paraclinical features are explained.

[Papillary carcinoma developing in thyroglossal duct cyst. Apropos of 2 cases].

The authors report two cases of papillary carcinoma of a thyreoglossal duct cyst. In both cases, the thyroïd gland was normal. Clinical manifestations are not specific and the diagnosis is usually made by histopathologic examination which reveals in the majority of cases a papillary carcinoma.