[Current aspects of malarial chemoresistance of subjects autochthonous in the OCCGE countries (West Africa)].

Within the context of the monitoring of malaria drug resistance in the countries of the OCCGE, a workshop has been organized in order to sum up the surveys carried out by the national teams. For active or passive monitoring mainly the in vivo tests have been used. The native population, mainly school children, was studied.

[Preliminary epidemiological study of dracunculosis in the southwest of Burkina Faso].

An epidemiologic survey was carried out before the setting up of an applied research project on dracunculiasis control through three strategies. The data were collected by house-to-house visits and from family cards. The overall incidence rate was 10.

[The role of malaria in febrile diseases in the urban environment of Ouagadougou (Burkina Faso, West Africa)].

We studied from January to December 1988 the part played by malaria in the etiology of febrile diseases observed in three community clinics of Ouagadougou city (Burkina Faso, West Africa). The diagnosis of malaria attacks was based on the association of a body temperature equal or above 38 degrees C and a parasite density equal or above 10,000 parasitized red blood cells per mm3. We observed that fever attacks were primarily caused by malaria.

[Vaccination against malaria: initial trial with an ant-sporozoite vaccine, (NANP)3-TT (RO 40-2361) in Africa (Bobo-Dioulasso, Burkina Faso)].

The vaccine (NANP)3-TT is a synthetic peptide of the circumsporozoite protein (CS) of Plasmodium falciparum coupled to tetanus toxoid (TT) as protein carrier and adsorbed to aluminium hydroxide as adjuvant. The objectives of the study were to assess the immunogenicity and the protective efficacy of the vaccine in an area where malaria is endemic. The study was conducted in a zone of irrigated rice cultivation known as the Vallée du Kou to the North of Bobo-Dioulasso.

[Emergence of chloroquine-resistant malaria in West Africa: the case of Sokode (Togo)].

Within the framework of its surveillance of Plasmodium falciparum chloroquine sensitivity in eight West African countries (Benin, Burkina Faso, Côte d'lvoire, Mali, Mauritany, Niger, Senegal, and Togo) the Reference Centre for Chemoresistant Malaria (CRCP) at the Organization for Coordination and Cooperation to Control Major Endemic Diseases (O.C.C.

[Filarial multiparasitism in the savannah zone in Burkina Faso].

From june 1985 to may 1986, 1.209 consulting patients were examined for filariae in skin and blood. Among patients with microfilariae 17% had associations of filarial infections.

[Surveillance of the sensitivity of Plasmodium falciparum to chloroquine in Western Africa: value of in vivo tests using 5 and 10 mg/kg].

Studies on the in vivo sensitivity of Plasmodium falciparum strains to chloroquine were carried out on shrub savanna areas of Burkina Faso, West Africa and were conducted from 1982 to 1986 in asymptomatic malarial school children. From the result of 431 in vivo tests using a single dose of only 5 or 10 mg/kg b. w.

[The OCCGE (Organisation de Coordination et de Coopération pour la Lutte contre les Grandes Endémies) and the surveillance of the drug sensitivity of Plasmodium falciparum to antimalarials].

Spreading of chemoresistance from East Africa to Central Africa is a very worrying problem for Western Africa. In fact, chemotherapy of febrile attacks is at present admitted as malaria control strategy in the framework of Primary Health Care. This new strategy is based on the fact that commonly used antimalarial drugs as chloroquine are surely efficacious.

The Beffa form of Simulium soubrense of the S. damnosum complex in Togo and Benin.

The Beffa form of Simulium soubrense Vajime & Dunbar, a member of the S. sanctipauli sub-complex of the S. damnosum complex, was found breeding throughout rivers in the Togo-Benin Gap, as far north as 9 degrees 30'N.

[Longitudinal study of Cyclopidae, intermediary hosts of the Guinea worm in the Sudano-Sahelian area (Burkina Faso)].

During 18 months covering two annual rainy seasons, 338 monthly water samples were taken in 29 ponds of two dracunculosis endemic villages of south-western Burkina Faso. The dynamics of ponds inhabited by Cyclopidae has been surveyed as far as their densities and their species are concerned. We identified a total number of 17 species from 6 genera of which the decreasing order in frequency is: Thermocyclops, Mesocyclops, Metacyclops, Cryptocyclops, Microcyclops and Allocyclops.

[Dracunculosis, a scourge eradicated from 3 villages of Burkina Faso through health education].

We carried out a dracunculiasis control study through health education in three southwestern hyperendemic villages of Burkina Faso. The villages were organized in the framework of Primary Health Care. Two years after the beginning of health education the sickness was eradicated.

[Dracunculosis: beliefs and attitudes of populations in the endemic zone of the savannah (Burkina-Faso)].

For years, most of the authors propose the sinking of wells as the only method of dracunculiasis control. However, this measure did not lead to the eradication of this very vulnerable endemic scourge in West Africa. Our research has concerned the collection of epidemiologic and socio-medical data close to the housewives.

[Critical study of an interdisciplinary survey of urinary schistosomiasis in Burkina Faso].

We consider an approach to built on a score summarizing some demographic, social, geographic and parasitologic data for purpose of measuring the health impact of schistosomiasis. Operational definitions are given for the social, ecological and medical variables and for the survey design. Twenty villages from the Bam-Kongoussi district were kept for the survey, giving a sample of 11,396 peoples.