Publications by authors named "Ouafae Mkinsi"

Objectives: The aim of this study was to determine the therapeutic maintenance level of methotrexate for rheumatoid arthritis patients enrolled in the Moroccan biotherapy registry and to identify predictive factors for discontinuing MTX treatment.

Methods: A cross-sectional study was conducted using the baseline data of the Moroccan biotherapy registry for RBSMR (a multicentric study that aims to evaluate tolerance of biological therapy on patients affected with rheumatic diseases). Demographics and disease features were compared using descriptive statistics.

View Article and Find Full Text PDF
Article Synopsis
  • Before starting biotherapy for rheumatic diseases, patients should be screened for latent tuberculosis infection (LTBI), and a study was conducted to assess the prevalence of LTBI in Moroccan patients with rheumatoid arthritis (RA) and spondyloarthritis (SpA).
  • The study included 259 patients (94 with RA and 165 with SpA) and found an overall LTBI prevalence of 21.6%, with higher rates in SpA (24.8%) compared to RA (15.9%).
  • Demographic and clinical characteristics showed no significant differences between LTBI-positive and negative patients, indicating that being in a TB-endemic country like Morocco presents a notable risk for both RA and SpA patients.
View Article and Find Full Text PDF

Introduction: the aim of our study is to determine, from data of the Moroccan register of biotherapies, the factors influencing the choice of the first prescribed biological treatment.

Methods: cross-sectional multicenter study including rheumatoid arthritis patients who were initiated the first biological treatment either: Rituximab, an anti-TNF, or Tocilizumab. The determinants related to the patient and disease have been gathered.

View Article and Find Full Text PDF