An INS/WiFi Indoor Localization System Based on the Weighted Least Squares.

For smartphone indoor localization, an INS/WiFi hybrid localization system is proposed in this paper. Acceleration and angular velocity are used to estimate step lengths and headings. The problem with INS is that positioning errors grow with time.

The kinases male germ cell-associated kinase and cell cycle-related kinase regulate kinesin-2 motility in Caenorhabditis elegans neuronal cilia.

Kinesin-2 motors power anterograde intraflagellar transport (IFT), a highly ordered process that assembles and maintains cilia. However, it remains elusive how kinesin-2 motors are regulated in vivo. Here, we performed forward genetic screens to isolate suppressors that rescue the ciliary defects of OSM-3-kinesin (homolog of mammalian homodimeric kinesin-2 KIF17) mutants in Caenorhabditis elegans.

Tuning defects in oxides at room temperature by lithium reduction.

Defects can greatly influence the properties of oxide materials; however, facile defect engineering of oxides at room temperature remains challenging. The generation of defects in oxides is difficult to control by conventional chemical reduction methods that usually require high temperatures and are time consuming. Here, we develop a facile room-temperature lithium reduction strategy to implant defects into a series of oxide nanoparticles including titanium dioxide (TiO), zinc oxide (ZnO), tin dioxide (SnO), and cerium dioxide (CeO).

HNA-3a and HNA-3b antigens among 9 ethnic populations and the Han population in Southwest China.

Background: Human neutrophil antigen 3 (HNA-3) is encoded by the SLC44A2 gene. Antibodies against HNAs can cause severe, often fatal, transfusion reactions, known as transfusion-related acute lung injury, and neonatal neutropenia. We explored the 2 common HNA-3 variants in 9 ethnic populations residing in Sichuan and Yunnan provinces of China as compared to the Han population.

Migration of Q Cells in Caenorhabditis elegans.

During C. elegans larval development, the Q neuroblasts produce their lineage by three rounds of divisions along with continuous cell migrations. Their neuronal progeny is dispersed from the pharynx to the anus.

Positive relationship between species richness and aboveground biomass across forest strata in a primary Pinus kesiya forest.

Both biodiversity and biomass are important variables in forest ecosystems, and the relationship between them is critical for ecosystem functioning and management. The primary Pinus kesiya forest is increasingly threatened by human disturbance in Yunnan Province. We observed that species richness had a positive impact on aboveground biomass across all forest vegetation layers, and this relationship was strongest in the herb layer.

Fabrication and application of noble metal nanoclusters as optical sensors for toxic metal ions.

Atomically precise noble metal nanoclusters with ultrasmall physical sizes in the subnanometer range have emerged as a new class of probing fluorophores and have attracted considerable research interest because of their intrinsic physical, chemical, optical, biological, and electrical properties, such as stability, biocompatibility, and molecule-like photoluminescence. In comparison with traditional fluorophores such as organic dyes and quantum dots, noble metal nanoclusters have significant advantages, including low toxicity toward the environment and biological tissues, high stability when exposed to irradiation, and small size, that make them more suitable for biological sensing or biological labeling applications. Several reviews have summarized the fabrication of noble metal nanoclusters, including gold, silver, copper, and bimetallic nanoclusters.

LINC00152 down-regulated to enhance MCL1 expression and promote gastric cancer cells proliferation.

The present work aimed to probe into the effect of long non-coding RNA (lncRNA) LINC00152 on gastric cancer (GC) cells proliferation by regulating and its target gene Transfected si-LINC00152 was used to down-regulate LINC00152, and cells proliferation was measured by the cell counting kit-8 (CCK-8) assay. Cell apoptosis and cell cycle were analyzed by flow cytometry (FCM). Besides, we also detected the potential functional effects of differential expression of LINC00152 using nude mouse xenograft model.

Ultra-low-temperature growth of CdS quantum dots on g-CN nanosheets and their photocatalytic performance.

CdS quantum dots deposited on carbon nitride (g-CN) nanosheets have been synthesized by ultra-low temperature (-60 °C) liquid phase precipitation reactions. The obtained CdS quantum dots were uniformly distributed on the surface of the g-CN nanosheets with an average diameter of 5 nm. Correspondingly, CdS/g-CN exhibits a highly enhanced photocatalytic performance.

The relationship between species richness and aboveground biomass in a primary Pinus kesiya forest of Yunnan, southwestern China.

The relationship between biodiversity and biomass is an essential element of the natural ecosystem functioning. Our research aims at assessing the effects of species richness on the aboveground biomass and the ecological driver of this relationship in a primary Pinus kesiya forest. We sampled 112 plots of the primary P.

Sham Feeding with Bacon Does Not Alter Transit Time or Complete Examination Rate During Small Bowel Capsule Endoscopy.

Background: During capsule endoscopy (CE) studies, the complete examination rate (CER) can be increased by prolonging capsule battery life or reducing gastric transit time (GTT) and/or small bowel transit time (SBTT). However, despite enhanced battery life, 10% of studies remain incomplete. Previously studied interventions to reduce SBTT and enhance CER have produced conflicting results.

Ultrathin two-dimensional metals with fully exposed (111) facets.

Large-size ultrathin two-dimensional (2D) metals with a fully exposed (111) surface have been synthesized by a heat-pressing process. As a result of the compact (111) surface arrangement, an ultrathin Pt 5 nm 2D metal exhibits a superior methanol electro-oxidation performance than an as-sputtered Pt 5 nm thin film (1.8, 2.

The current incidence, prevalence, and residual risk of hepatitis B viral infections among voluntary blood donors in China.

Background: There are few data available on the prevalence, incidence, and residual risk of transfusion-transmitted HBV (TT-HBV) infections among Chinese blood donors. This study investigated the demographic characteristics of blood donors, as well as the prevalence, incidence, and residual risk (RR) of TT-HBV infections in six large blood centers in different regions of China.

Methods: The demographic characteristics and HBV screening test results of blood donors from six blood centers in different regions in China were collected and analyzed.

Polydopamine deposition with anodic oxidation for better connective tissue attachment to transmucosal implants.

Background And Objective: Nowadays, most designs for the transmucosal surface of implants are machined-smooth. However, connective tissue adhered to the smooth surface of an implant has poor mechanical resistance, which can render separation of tissue from the implant interface and induce epithelial downgrowth. Modification of the transmucosal surface of implants, which can help form a good seal of connective tissue, is therefore desired.

Identification of the novel allele, HLA-DRB1*09:30, by sequence-based high resolution typing.

HLA-DRB1*09:30 shows a single nucleotide difference from DRB1*09:01:02 at nucleotide 250 (CGG→TGG).

The dinoflagellate Akashiwo sanguinea will benefit from future climate change: The interactive effects of ocean acidification, warming and high irradiance on photophysiology and hemolytic activity.

Due to global climate change, marine phytoplankton will likely experience low pH (ocean acidification), high temperatures and high irradiance in the future. Here, this work report the results of a batch culture experiment conducted to study the interactive effects of elevated CO, increased temperature and high irradiance on the harmful dinoflagellate Akashiwo sanguinea, isolated at Dongtou Island, Eastern China Sea. The A.

An interval chance-constrained fuzzy modeling approach for supporting land-use planning and eco-environment planning at a watershed level.

An interval chance-constrained fuzzy land-use allocation (ICCF-LUA) model is proposed in this study to support solving land resource management problem associated with various environmental and ecological constraints at a watershed level. The ICCF-LUA model is based on the ICCF (interval chance-constrained fuzzy) model which is coupled with interval mathematical model, chance-constrained programming model and fuzzy linear programming model and can be used to deal with uncertainties expressed as intervals, probabilities and fuzzy sets. Therefore, the ICCF-LUA model can reflect the tradeoff between decision makers and land stakeholders, the tradeoff between the economical benefits and eco-environmental demands.

Microtubule-binding protein FOR20 promotes microtubule depolymerization and cell migration.

Microtubules are highly dynamic filaments assembled from αβ-tubulin heterodimers and play important roles in many cellular processes, including cell division and migration. Microtubule dynamics is tightly regulated by microtubule-associated proteins (MAPs) that function by binding to microtubules or free tubulin dimers. Here, we report that FOR20 (FOP-related protein of 20 kDa), a conserved protein critical for ciliogenesis and cell cycle progression, is a previously uncharacterized MAP that facilitates microtubule depolymerization and promotes cell migration.

α5β1-Integrin promotes tension-dependent mammary epithelial cell invasion by engaging the fibronectin synergy site.

Tumors are fibrotic and characterized by abundant, remodeled, and cross-linked collagen that stiffens the extracellular matrix stroma. The stiffened collagenous stroma fosters malignant transformation of the tissue by increasing tumor cell tension to promote focal adhesion formation and potentiate growth factor receptor signaling through kinase. Importantly, collagen cross-linking requires fibronectin (FN).

Enhanced Electrocatalytic Activity for Water Splitting on NiO/Ni/Carbon Fiber Paper.

Large-scale growth of low-cost, efficient, and durable non-noble metal-based electrocatalysts for water splitting is crucial for future renewable energy systems. Atomic layer deposition (ALD) provides a promising route for depositing uniform thin coatings of electrocatalysts, which are useful in many technologies, including the splitting of water. In this communication, we report the growth of a NiO/Ni catalyst directly on carbon fiber paper by atomic layer deposition and report subsequent reduction and oxidation annealing treatments.

WASP-Arp2/3-dependent actin polymerization influences fusogen localization during cell-cell fusion in embryos.

Cell-cell fusion is essential for development and physiology. Actin polymerization was implicated in the fusogen EFF-1 engagement in a reconstituted cell culture system, and the actin-binding protein spectraplakin links EFF-1 to the actin cytoskeleton and promotes cell-cell fusions in larvae. However, it remains unclear whether and how fusogens and the actin cytoskeleton are coordinated in embryos.

Centriole translocation and degeneration during ciliogenesis in neurons.

Neuronal cilia that are formed at the dendritic endings of sensory neurons are essential for sensory perception. However, it remains unclear how the centriole-derived basal body is positioned to form a template for cilium formation. Using fluorescence time-lapse microscopy, we show that the centriole translocates from the cell body to the dendrite tip in the sensory neurons.

Economic Evaluation of Implant-Supported Overdentures in Edentulous Patients: A Systematic Review.

Purpose: Edentulous patients benefit significantly from implant-supported overdenture prostheses. The purpose of this systematic review was to evaluate the cost-effectiveness of implant-supported overdentures (IODs) for edentulous patients.

Materials And Methods: The search was limited to studies written in English and included an electronic and manual search through MEDLINE (Ovid, 1946 to November 2015), Embase (Ovid, 1966 to November 2015), Cochrane Central Register of Controlled Trials (CENTRAL) (to November 2015), and PubMed (to November 2015).

WMJ-8-B, a novel hydroxamate derivative, induces MDA-MB-231 breast cancer cell death via the SHP-1-STAT3-survivin cascade.

Background And Purpose: Histone deacetylase (HDAC) inhibitors have been demonstrate to have broad-spectrum anti-tumour properties and have attracted lots of attention in the field of drug discovery. However, the underlying anti-tumour mechanisms of HDAC inhibitors remain incompletely understood. In this study, we aimed to characterize the underlying mechanisms through which the novel hydroxamate-based HDAC inhibitor, WMJ-8-B, induces the death of MDA-MB-231 breast cancer cells.

Ultralight, scalable, and high-temperature-resilient ceramic nanofiber sponges.

Ultralight and resilient porous nanostructures have been fabricated in various material forms, including carbon, polymers, and metals. However, the development of ultralight and high-temperature resilient structures still remains extremely challenging. Ceramics exhibit good mechanical and chemical stability at high temperatures, but their brittleness and sensitivity to flaws significantly complicate the fabrication of resilient porous ceramic nanostructures.