Publications by authors named "Otto Schofer"
Article Synopsis
- Neuronal ceroid lipofuscinoses (NCL) is a serious childhood neurodegenerative disease that presents with symptoms like retinopathy, dementia, and epilepsy, and includes ten different forms.
- Two infants, a brother and sister, were diagnosed with infantile NCL (CLN 10 disease) and exhibited severe seizures and respiratory issues just after birth, highlighting specific clinical and imaging characteristics.
- Clinicians should consider CLN10 as a potential diagnosis in newborns with severe epilepsy and respiratory problems, raising important ethical considerations regarding treatment options due to the disease's severity and limited effectiveness of current therapies.
Breast-feeding plays an important role for the development of the newborn. Non-breast fed premature born infants show a significantly higher risk of developing diseases like infantile diarrhoea and necrotizing enterocolitis. In this study, the content of neurotrophic factors and cytokines, which might influence the postnatal development of the enteric nervous system (ENS), was determined in human breast milk.
View Article and Find Full Text PDF