Publications by authors named "Otto Lindahl"
Article Synopsis
- Mast cells are key players in the immune system, located in mucosal tissues, and help defend against infections, particularly from bacteria like Salmonella Typhimurium (S.Tm).
- The study reveals that mast cells can differentiate between extracellular bacteria and those that invade host cells, adjusting their cytokine secretion in response to the type of infection.
- Invasive S.Tm leads to a strong inflammatory response in mast cells through a two-step activation process involving the recognition of bacterial factors and cellular signaling pathways, which also enhances the survival and maturation of macrophages.
