Publications by authors named "Otto H Valdes-Martinez"
The Effects of Preimplantation Genetic Testing for Aneuploidy (PGT-A) on Patient-Important Outcomes in Embryo Transfer Cases: A Meta-Analysis.
J Reprod Infertil
January 2022
Article Synopsis
- - The study aimed to assess how preimplantation genetic testing for aneuploidy (PGT-A) affects reproductive outcomes after in vitro fertilization (IVF).
- - Ten studies involving 2630 embryo transfers were analyzed, showing no significant overall improvement in live birth or miscarriage rates with PGT-A, but a potential benefit for older women.
- - The authors recommend caution in promoting PGT-A for all couples since the benefits may not outweigh the costs for everyone, particularly those not of advanced maternal age.
Background: The ovarian function and therefore the ovarian reserve may be compromised by the pathogenesis of autoimmune diseases of which, Hashimoto's thyroiditis (HT) is the most common in women of reproductive age. Furthermore, a prolonged reduction in thyroid hormone concentration results in a broad spectrum of reproductive alteration. Previous reports in the literature have been controversial regarding the impact of hypothyroidism and alterations in the ovarian reserve.
View Article and Find Full Text PDFObjective:: Investigate the possible effect of an acute sildenafil dose in asthenozoospermic patients.
Methods:: We ran this experimental, descriptive, prospective and non-blinded study in 32 patients diagnosed with asthenozoospermia according to the WHO criteria, after two consecutive semen analyses (samples 1 and 2), and we asked them to provide a new semen sample two weeks after the initial exams (sample 3). One hour prior to the semen collection, we gave the patients 100mg oral sildenafil.
Objective: To identify the effect of apoptotic sperm elimination with MACS in patients that require IVF.
Methods: An experimental, cross-sectional, descriptive, prospective and non-blinded study of diagnostic tests performed in patients who required IVF and ICSI from July 2011 to July 2012. Ninety-two couples participated according to the treatment administered to the semen sample; in the control group: the samples were subjected only to density gradients before ICSI, in the study group: the same procedure was performed plus the addition of the MACS technique.