Publications by authors named "Otilia Georgescu"

Article Synopsis
  • The study examined 1000 lower-risk myelodysplastic syndrome (MDS) patients from the European LeukaemiaNet MDS registry, validating the revised International Prognostic Scoring System (IPSS-R) for better prognostic assessment.
  • Key findings included that lower quality of life scores and high co-morbidity indices were linked to poorer survival outcomes, confirming previous prognostic factors.
  • The IPSS-R outperformed the original IPSS in predicting disease progression and survival, with 70% of patients receiving specific treatments and supportive care shortly after diagnosis.
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The microbial etiology of gingivitis and marginal periodontitis is unanimously accepted, but several other factors have to be considered. There are many systemic conditions with unvarying manifestations at the level of the gums and deep periodontium; leukemias have varying rates of development, and in most cases a reserved prognosis. In leukemias, periodontal lesions are caused by various microbial factors, coupled with immunological modifications characteristic of the systemic condition and sometimes exacerbated by loco-regional leukocyte infiltration.

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