In silico design of a novel hybrid epitope-based antigen harboring highly exposed immunogenic peptides of BamA, OmpA, and Omp34 against Acinetobacter baumannii.

Acinetobacter baumannii, is among the highest priority bacteria according to the WHO categorization which necessitate the exploration of alternative strategies such as vaccination. OmpA, BamA, and Omp34 are assigned as appropriate antigens to serve in vaccine development against this pathogen. Experimentally validated exposed epitopes of OmpA and Omp34 along with selected exposed epitopes predicted by an integrative in silico approach were represented by the barrel domain of BamA as a scaffold.

Prevalence and Predictors of Infection in Psychiatric Inpatients in Fars Province, Southern Iran.

Background: Psychiatric patients are at increased risk of exposure to infection, which may be linked to their living facilities and behaviors. Limited knowledge on the prevalence of infection and its associated risk factors in psychiatric patients are available to the international medical communities. Thus, the aim of the current study was to assess seroprevalence of and its associated risk factors in psychiatric inpatients in Fars Province, southern Iran.