The thrombus proteome in stroke reveals a key role of the innate immune system and new insights associated with its etiology, severity, and prognosis.

Background: Nowadays little is known about the molecular profile of the occluding thrombus of patients with ischemic stroke.

Objectives: To analyze the proteomic profile of thrombi in patients who experienced an ischemic stroke in order to gain insights into disease pathogenesis.

Methods: Thrombi from an exploratory cohort of patients who experienced a stroke were obtained by thrombectomy and analyzed by sequential window acquisition of all theoretical spectra-mass spectrometry.

Balloon guide catheter improvements in thrombectomy outcomes persist despite advances in intracranial aspiration technology.

Background: First-pass effect (FPE) has been established as a key metric for technical success and strongly correlates with better clinical outcomes. Most data supporting improved outcomes with the use of a balloon guide catheter (BGC) predate the advent of last-generation large-bore intracranial aspiration catheters. We aim to evaluate the impact of BGC in FPE and clinical outcomes in a large cohort of patients treated with contemporary technology.

Half bolus dose of intravenous abciximab is safe and effective in the setting of acute stroke endovascular treatment.

Background: A stent is often necessary for the treatment of stroke. In such cases,it is essential for the patient to have antiplatelet therapy. There are several methods of antiaggregation, such as oral loading doses of aspirin and clopidogrel, intravenous aspirin, or intravenous glycoprotein IIb/IIIa receptor antagonists, such as abciximab.

Unprotected carotid artery stenting in symptomatic patients with high-grade stenosis: results and long-term follow-up in a single-center experience.

Background And Purpose: The use of cerebral protection during CAS is an extended practice. Paradoxically it is open to question because it can lead to potential embolic complications. The aim of this study was to evaluate the safety and efficacy of CASWPD in patients with severe symptomatic carotid artery stenosis.

Treatment of dural arteriovenous fistulas presenting as pulsatile tinnitus.

Objective: To describe the clinical picture and treatment of dural arteriovenous fistulas (DAVFs) presenting as pulsatile subjective tinnitus.

Study Design: Review of prospectively collected data.

Setting: Academic referral center.

[Acute renal failure and hypertension].

Ischemic nephropathy could be complicated with hypertension and acute worsening of chronic renal failure secondary to ACE inhibitors or AT receptor antagonist treatments and arterial occlusion. We describe a patient with bilateral renal artery stenosis and hypertension treated with ATI receptor antagonist (valsartan) that developed rapid worsening of renal function that required dialysis. Percutaneous transluminal renal artery angioplasty and stenting, complemented with hydratation and valsartan suppression achieves rapid and sustained recovery of renal function.

[Antioxidative state and lipid peroxidation in erectile dysfunction: preliminary study].

Objective: The aims of this study were to analyze the cavernosal tissue metabolic status of patients with vascular and psychogenic impotence and attempt to establish metabolic differences between these types of erectile dysfunction.

Methods: 103 patients were classified according to the type of erectile dysfunction into group A (vascular) and group B (psychogenic). Diagnosis was based on clinical history, physical examination, intracavernosal injection test, penile echo-doppler assessment, cavernosography-cavernosometry and nocturnal penile test.

Percutaneous embolization for erectile dysfunction due to venous leakage: prognostic factors for a good therapeutic result.

Objectives: To identify prognostic parameters for patient outcome after embolization for erectile dysfunction (ED) due to venous leakage (VL).

Methods: 23 patients presenting with ED due to pure venous leakage were selected. Intracavernous pharmacological testing, Doppler ultrasound, dynamic cavernosography-cavernosometry and cavernous oxygen tension were done.