Objective: To evaluate the effect of maturation and ageing on oestrogen-induced functional hypertrophy of the female rabbit bladder.
Materials And Methods: Twenty female rabbits were separated into two groups of 10 each by age, young (immature) and old rabbits and each age group was subdivided into three subgroups. The rabbits in subgroup 1 were controls, subgroup 2 were ovariectomized (Ovx) and subgroup 3 were Ovx and received 17-beta oestradiol (1 mg/kg/day) by a subcutaneous slow-release tablet implant.