In vitro and in vivo assessment of oxygenator blood volume for the prediction of clot formation in an ECMO circuit (theory and validation).

Introduction: Clotting is one of the major causes of mortality and morbidity during extracorporeal membrane oxygenation (ECMO). A large meta-analysis study suggests that 29% of patients require the oxygenator to be replaced during ECMO. As clots usually form in the oxygenator, the oxygenator blood volume (OXBV) decreases over time.

Exercise addiction in Spanish athletes: Investigation of the roles of gender, social context and level of involvement.

Background And Aims: In nomothetic research exercise addiction is studied on the basis of symptoms which are most often linked to exercise volume. However, other factors may also affect individuals' susceptibility to the disorder. The aim of this research was to examine the influence of gender, social context (team or individual sport), and level of athletic training on symptoms of exercise addiction.

Hardiness in professional Spanish firefighters.

As a high risk, physically demanding, and stressful profession, firefighting presents an ideal context for the study of hardiness. Hardiness of professional Spanish firefighters was assessed. Participants (53 firefighters; M age = 36.

Mindfulness training online for stress reduction, a global measure.

According to the World Health Organization (WHO), stress-related chronic diseases are the main source of death in developed countries. During the last decade, e-mental health, telepsychology or telepsychiatry interventions are showing its growing potential due to the gradual global adoption of the internet and mobile phone technologies. A significant number of studies have concluded that mindfulness helps to reduce physical and psychological symptoms of stress related to various health concerns and that it is a psychological skill that can be trained.

Hemolytic and thrombocytopathic characteristics of extracorporeal membrane oxygenation systems at simulated flow rate for neonates.

Objective: A state-of-the-art centrifugal pump combined with hollow-fiber oxygenator for extracorporeal membrane oxygenation has potential advantages such as smaller priming volumes and decreased potential to cause tubing rupture as compared with the traditional roller head/silicone membrane systems. Adoption of these state-of-the-art systems has been slow in neonates as a result of past evidence of severe hemolysis that may lead to renal failure and increased mortality. Extracorporeal systems have also been linked to platelet dysfunction, a contributing factor toward intracranial hemorrhage, a leading cause of infant morbidity.

Validation of the CAS neonatal NIRS system by monitoring vv-ECMO patients: preliminary results.

The CAS neonatal NIRS system determines absolute regional brain tissue oxygen saturation (SnO2) and brain true venous oxygen saturation (SnvO2) non-invasively. Since NIRS-interrogated tissue contains both arterial and venous blood from arterioles, venules, and capillaries, SnO2 is a mixed oxygen saturation parameter, having values between arterial oxygen saturation (SaO2) and cerebral venous oxygen saturation (SvO2). To determine a reference for SnO2, the relative contribution of SvO2 to SaO2 drawn from a brain venous site vs.

Comparison of the effect of venovenous versus venoarterial extracorporeal membrane oxygenation on renal blood flow in newborn lambs.

Unlabelled: Venovenous extracorporeal membrane oxygenation (VV ECMO) using double lumen catheters is an alternative to venoarterial (VA) ECMO and allows for total blood flow using the patient's cardiac output in comparison to partial blood flow provided during VA ECMO.

Objective: To compare the effects of VV versus VA ECMO on renal blood flow.

Design: Prospective study.

The use of intratracheal pulmonary ventilation and partial liquid ventilation in newborn piglets with meconium aspiration syndrome.

OBJECTIVE: To determine whether intratracheal pulmonary ventilation (ITPV) combined with partial liquid ventilation (PLV) improves oxygenation and ventilation at lower mean airway and peak inspiratory pressures when compared with conventional mechanical ventilation in a piglet model of meconium aspiration syndrome. DESIGN: Prospective, randomized, interventional study. SETTING: Animal Research Laboratory at the Children's National Medical Center, Washington, DC.

Improved oxygenation with reduced recirculation during venovenous ECMO: comparison of two catheters.

Objectives: To determine whether the new double-lumen catheter made by OriGen Biomedical (Austin, TX) for venovenous (VV) extracorporeal membrane oxygenation (ECMO) would reduce recirculation and improve oxygenation during VV ECMO when compared with the Kendall double-lumen catheter (Kendall Healthcare Products, Mansfield, MA).

Design: Prospective intervention study.

Setting: The animal research laboratory at Children's National Medical Center, Washington, DC.

Continuous blood gas monitoring using an in-dwelling optode method: comparison to intermittent arterial blood gas sampling in ECMO patients.

Introduction: The ability to measure postmembrane arterial blood gases is essential in the management of critically ill neonates treated with extracorporeal membrane oxygenation (ECMO). A new technology using, the Paratrend 7 system (Diametrics Medical, High Wycombe,UK) allows for continuous measurement of pH, PCO(2) and PO(2), and calculates oxygen saturation, bicarbonate, and base excess.

Objective: To evaluate and compare the results of continuous blood gas measurement using the Paratrend 7 system with a standard system of blood gas analysis in our intensive care unit.

Continuous blood gas monitoring using an in-dwelling optode method: clinical evaluation of the Neotrend sensor using a luer stub adaptor to access the umbilical artery catheter.

Introduction: Arterial blood gases are essential in the management of critically ill neonates. A new technology using the Neotrend system (Diametrics Medical) allows for continuous measurement of pH, PaCO(2), and PaO(2), and calculates oxygen saturation, bicarbonate, and base excess.

Objective: To evaluate and compare the results of continuous blood gas measurement using the Neotrend system with a standard system of blood gas analysis in our intensive care unit.