Publications by authors named "Osvaldo J Rivera Gonzales"
Mol Cell Endocrinol
August 2024
Article Synopsis
- Researchers used a 3-D in vitro culture model to study how the hormones 17β-estradiol and testosterone affect fat cell development in human adipose-derived stem cells (hASCs) from both male and female patients.
- The study tested doses of 100 nM and 500 nM of the hormones during two phases of adipogenic maturation, finding that 17β-estradiol effectively reduced fat storage in female cells while promoting fat breakdown in the later stage, but had little effect on male cells.
- Results indicate that 17β-estradiol can significantly help prevent fat accumulation in female hASCs, underscoring differences in response to sex hormones between genders.
