Publications by authors named "Osmonov D"

Background: Inflatable penile prosthesis (IPP) insertion is recommended for the treatment of patients with Peyronie's disease (PD) and significant erectile dysfunction (ED); adjunctive procedures can be used for residual curvature after IPP placement.

Aim: To assess the management of penile curvature correction in PD patients undergoing IPP procedures within a large multinational, multicenter cohort.

Methods: A retrospective analysis was conducted on PD patients treated with IPP by 11 experienced prosthetic surgeons.

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  • The study aimed to analyze pre- and intraoperative factors influencing the integrity of corporal bodies after placing an inflatable penile prosthesis (IPP), focusing on the occurrence of intraoperative and postoperative complications.
  • Researchers reviewed a database of over 5,400 IPP surgeries conducted between 2016 and 2021, identifying significant predictors for complications linked to corporal integrity.
  • Key predictors for complications included revision surgery, older age, and medical conditions like coronary artery disease or peripheral vascular disease, indicating the need for consideration of these factors during IPP placement to reduce risks.
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  • Conversions from robot-assisted partial nephrectomy to more invasive surgeries happen in about 1-5% of cases, and this study looks at what could predict these conversions.
  • The research analyzed 2,549 patients operated on by 25 surgeons, finding a 3.5% conversion rate linked to factors like older age, higher BMI, tumor size, and the surgeon’s experience.
  • The study concludes that both patient characteristics and surgical expertise significantly impact the likelihood of conversion, suggesting that better training could enhance outcomes and allow for more kidney-sparing procedures.
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  • - The study aimed to analyze factors affecting postoperative renal function (PRF) following robot-assisted partial nephrectomy for patients with multiple kidney tumors, using data from 132 surgeries and assessing both patient and surgical influences on outcomes.
  • - Key findings included that most patients had two tumors, the average surgery lasted 175 minutes, and that the majority of surgeries met trifecta criteria, indicating successful outcomes in terms of cancer control, renal preservation, and complications.
  • - Factors such as warm ischemia time, body mass index (BMI), and preoperative kidney function were found to impact kidney function loss post-surgery, with BMI and comorbidities being significant predictors of acute kidney injury during hospitalization.
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  • Penile prosthesis implantation (PPI) is an effective treatment for severe erectile dysfunction when other therapies fail, but it's complicated for patients with corporal fibrosis (CF).
  • Imaging techniques like ultrasound and MRI are essential in planning for PPI, helping to assess the severity of fibrosis before surgery.
  • The review emphasizes that careful preoperative imaging can enhance surgical outcomes and minimize complications in patients with CF.
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  • * The authors developed a new, budget-friendly material system using sodium alginate hydrogel and coconut fat that allows for accurate adjustment of imaging properties for CT and ultrasound independently.
  • * This innovative approach is particularly advantageous in low-resource settings, as the materials are affordable (less than $1 USD/kg) and easily accessible, enabling the creation of versatile phantoms to improve surgical training and patient care.
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  • - The study aimed to identify factors influencing the length of penile implants in men undergoing primary inflatable penile prosthesis (IPP) placement at multiple surgical centers from July 2016 to July 2021.
  • - Findings revealed that older age, Asian ethnicity, history of radical prostatectomy, and the infrapubic surgical approach were linked to shorter implant lengths, while Black or African American ethnicity was associated with longer implants.
  • - Understanding these associations can help doctors better counsel patients about potential implant lengths and set realistic expectations for postoperative outcomes.
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Background: Hypertrophic cardiomyopathy (HCM) is a genetic heart disease that can lead to heart failure, atrial fibrillation, and ischaemic symptoms. Managing patients with HCM and ischaemic symptoms is challenging, and several treatment options have been proposed.

Case Summary: A 30-year-old male patient presented with severe chest pain that had been ongoing for more than 30 min at rest.

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Ischemic priapism is a urological emergency which may lead to irreversible erectile dysfunction. One of the accepted treatments is penile prosthesis implantation. Given the scarcity of studies directly comparing timing of penile prosthesis insertion after ischemic priapism, consensus remains elusive.

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  • A study was conducted to investigate how climate variations influence the risk of infections in patients receiving inflatable penile prosthesis (IPP) surgery across multiple international medical centers.
  • The research analyzed data from 5,289 patients, finding no statistically significant correlation between the season or month of surgery, daily temperature, humidity, or dew point, and the occurrence of infections, which were relatively low at 1.9%.
  • The results suggest that urologists don't need to adjust infection prevention strategies based on climate conditions when performing IPP surgeries.
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Objective: To assess the difference in outcomes between single dilation (SingD) and sequential dilation (SeqD) in primary penile implantation, hypothesizing that patients who undergo SeqD had higher rates of noninfectious complications.

Methods: We performed a multicenter, retrospective study of men undergoing primary inflatable penile prosthesis placement. Intraoperative complications and postoperative noninfectious outcomes were assessed between the two groups.

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The anterior ilioinguinal and the posterior Kocher-Langenbeck approach have long been the standard surgical approaches to the acetabulum. The last decade has witnessed the development of so-called intrapelvic approaches for anterior pathologies because they provide better exposure of the quadrilateral plate. Currently, the modified Stoppa approach and the pararectus approach are frequently used by surgeons for the treatment of acetabular fractures.

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Background: Prosthetic valve thrombosis (PVT) is a rare but one of the most dreaded complications of implanted mechanical valves. Although surgery is the first-line treatment modality particularly in symptomatic obstructive mechanical valve thrombosis, it is associated with high rates of morbidity and mortality. Thrombolytic therapy has also been used as an alternative to surgical treatment.

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Background: In 2017, a prospective multicenter, multinational, investigational pilot study was conducted examining outcomes using a novel surgical technique, the Mini-Jupette sling, for the management of erectile dysfunction (ED) patients with climacturia and/or minimal stress urinary incontinence (SUI) after prostate procedures. Climacturia has been reported in up to 64% of patients following radical prostatectomy (RP). We sought to report the 5-year outcomes from this original cohort to assess long-term safety and effectivity of the mini-jupette sling in the treatment of ED and concomitant mild SUI and/or climacturia.

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Background: Corporal fibrosis is known to result from prolonged priapism; however, the impact of the timing of penile prosthesis placement after priapism on complication rates is poorly understood.

Aim: We sought to evaluate the impact of timing of inflatable penile prosthesis (IPP) placement on complications in men with a history of ischemic priapism.

Methods: We performed a multicenter, retrospective cohort study of patients with a history of priapism undergoing IPP placement by 10 experienced implantation surgeons.

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Surgical implantation of an inflatable penile prosthesis (IPP) remains the gold-standard treatment for severe erectile dysfunction. The ideal surgical technique requires a thorough understanding of the relevant anatomy. This includes anatomic considerations related to, but not limited to, dissection and exposure of penoscrotal fasciae and tissues, corporal configuration, and abdominal structures.

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We aimed to understand the risks and benefits of post-inflatable penile prosthesis (IPP) implantation drainage and optimal duration. Our patients were divided into 3 groups: Group 1 (n = 114) had no drain placed, Group 2 had a drain placed for 24 h (n = 114) and Group 3 had a drain placed for 72 h (n = 117). Postoperative scrotal hematoma and prosthesis infection rates were compared between the groups.

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Objective: To evaluate the relationship between pre-operative PSA value, Ga-prostate-specific-membrane-antigen (PSMA) PET performance and oncologic outcomes after salvage lymph node dissection (sLND) for biochemical recurrent prostate cancer (PCa).

Patients And Methods: The study included 164 patients diagnosed with ≤2 pelvic lymph-node recurrence(s) of PCa documented on Ga-PSMA PET scan and treated with pelvic ± retroperitoneal sLND at 11 high-volume centres between 2012 and 2019. Pathologic findings were correlated to PSA values at time of sLND, categorized in early (<0.

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Background: Robot-assisted partial nephrectomy (RAPN) is a challenging procedure that is influenced by a multitude of factors.

Objective: To assess the impact of prior surgical experience on perioperative outcomes in RAPN.

Design Setting And Participants: In this retrospective multicenter study, results for 2548 RAPNs performed by 25 surgeons at eight robotic referral centers were analyzed.

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Purpose: Our aim was to determine if the AUA-recommended prophylaxis (vancomycin + gentamicin alone) for primary inflatable penile prosthesis surgery is associated with a higher infection risk than nonstandard regimens.

Materials And Methods: We performed a multicenter, retrospective study of patients undergoing primary inflatable penile prosthesis surgery. Patients were divided into those receiving vancomycin + gentamicin alone and those receiving any other regimen.

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Background: Systemic Lutetium-177 prostate-specific membrane antigen-617 radioligand therapy (Lu-177-PSMA-617-RLT) is a novel treatment approach in patients suffering from metastasized castration-resistant prostate cancer. Nonetheless, a therapeutic response may fail to appear in a proportion of patients. This study aims to identify routinely obtainable pre- and intratherapeutic parameters to allow a prediction of overall survival in patients receiving Lu-177-PSMA-617 radioligand therapy.

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Inflatable penile prostheses may be a solution for patients with erectile dysfunction. To our knowledge, no data exist regarding the effect of different surgical approaches used during implantation on the site of the corporotomy. The main purpose of this multicentre study was to investigate the influence of different surgical approaches on the corporotomy site.

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