[Clinical and laboratory studies of the hemorrhagic syndrome in hypo- and aplastic anemias].

Hemorrhagic manifestations were found in 142 (66.6%) out of 213 followed up patients with hypo- and aplastic anemia. Detailed clinical-laboratory study on the hemorrhagic syndrome was conducted in 58 of them.

[Study of the proliferative activity of the bone marrow cells in hypoplastic anemia and acute leukemia].

Autoradiographic investigations were carried out on bone marrow cells with thymidine H3 in patients with hypoplastic anemia and acute leukosis in hypoplastic phase. In all patients with hypoplastic anemia a considerable decrease of the labelled cells per cent was observed and in four of the patients in a period of exacerbation, two--in remission--no labelled cells were found. In patients with hypoplastic phase of acute leukosis the proliferative activity was absent.

Respiratory function in iron deficiency anaemia before and after treatment.

The present studies concern the basic ventilatory indices, the arterial blood gases, the indices of the acid-base balance and the indices of the alveolar-capillary diffusion (DLCO, SS, Dm, theta Vc) in anemia before and after treatment. Substantial changes are recorded after treatment mainly in DLCO, SS and theta Vc. These changes are predominantly due to changes in the concentration of Hb.