Retrospective evaluation of pathologic fractures in medication related osteonecrosis of the jaw.

The aim of this study was to focus on the MRONJ-related pathologic fractures, their incidence, and to analyze possible causative factors for their occurrence. Pathologic fracture in patients suffering frm MRONJ were identified, examined in detail, and the patient characteristics were evaluated. In 116 patients (73 female and 43 male; mean age 62.

The effect of chronic dental inflammation on development of Stage 0 medication-related osteonecrosis of the jaw.

Objective: The pathogenesis of medication-related osteonecrosis of jaw (MRONJ) is poorly understood. The aim of this prospective study was to determine the effect of chronic dental inflammation on the development of Stage 0 MRONJ based on histopathological findings.

Methods: The study involved patients with a history of bisphosphonate use and an indication for tooth extraction.