Publications by authors named "Osman Serhat Tokgoz"
Objectives: The aim of the study is to investigate the relationship of lipid subgroups with short-term mortality in acute stroke (AS).
Methods: This retrospective study included 698 patients with AS who presented within 24 h of symptom onset. A hemogram from peripheral venous blood samples was taken at admission.
Background: Characterized by demyelination, inflammation and axonal damage, multiple sclerosis (MS) is one of the most common disorders of central nervous system led by the immune system. There is an urgent and obvious need for biomarkers for the diagnosis and follow-up of MS.
Objective: To investigate serum levels of sestrin2 (SESN2), a protein that responds to acute stress, in MS patients.
Background: Multiple sclerosis (MS) is an inflammatory and neurodegenerative autoimmune chronic neurological disease. Currently, there are no effective serum biomarkers to verify MS diagnosis, to assess disease prognosis, and evaluate response to MS treatment.
Objective: The present study is a preliminary assessment of irisin and nesfatin-1 serum levels in patients with relapsing- remitting MS (RRMS).
Article Synopsis
- The study examines the connection between depression and inflammatory markers in patients who have experienced an acute ischemic stroke (AIS), focusing on whether inflammation increases the risk of stroke in those with major depression.
- Researchers aimed to analyze levels of specific inflammatory factors, including TNF-α, IL-1β, IL-18, BDNF, and NSE, in AIS patients and their relationship with major depression.
- Conducted at Necmettin Erbakan University in Turkey, the study found that a significant percentage (32.1%) of the 53 AIS patients had major depression, indicating a possible link between depression and increased inflammatory markers.
Background: Stroke patients with development of delirium have unfavorable outcomes, higher mortality, longer hospitalizations, and a greater degree of dependence after discharge. Studies suggest that delirium is associated with abnormal immunological responses and a resultant increase in inflammatory markers.
Objective: Our aim was to determine whether there is an entity relationship between delirium, inflammation and acute ischemic stroke (AIS).
Background: Cerebellar infarct is a rare condition with very nonspecific clinical features. The aim of this study was to assess the full spectrum of the clinical characteristics, neuroimaging findings and neurofunctional analyses of cerebellar infarction, and the relationship between them.
Materials And Methods: Data were collected from 59 patients admitted to our department during an 8-year period.
A Neuro-Behçet's Case Operated with the Intracranial Mass Misdiagnosis.
J Korean Neurosurg Soc
November 2012
Behçet's disease (BD) is an inflammatory systemic disorder with oral and genital ulcers, as well as ophthalmologic and cutaneous symptoms. Neurological manifestations in BD represent between 2.2% to 50% of the cases.
View Article and Find Full Text PDFBackground: Detection of paroxysmal atrial fibrillation (PAF) in acute ischemic stroke patients poses diagnostic challenge. The aim of this study was to predict the presence of PAF by means of 12-lead ECG in patients with acute ischemic stroke. Our hypothesis was that P-wave dispersion (P(d)) might be a useful marker in predicting PAF in patients with acute ischemic stroke.
View Article and Find Full Text PDFObjective: The goal of the study described here was to evaluate interictal heart rate variability (HRV) in young patients with epilepsy, a patient population in whom sudden unexpected death in epilepsy (SUDEP) is known to be more common.
Methods: Twenty-four-hour ambulatory ECG Holter recordings of 37 patients (15-40 years old) and 32 healthy controls were compared.
Results: All of the time domain indices (SDNN, SDANN, RMSSD, and HRV triangular index) were significantly suppressed (P<0.