Publications by Osman Buyuksen

Publications by authors named "Osman Buyuksen"

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Common complications in spinal muscular atrophy (SMA) type 1 after nusinersen treatment.

Yiğithan Güzin Osman Büyükşen Pınar Gençpınar Nihal Olgaç Dündar Figen Baydan

Turk J Pediatr

November 2024

Article Synopsis

Spinal muscular atrophy (SMA) is a genetic disorder leading to muscle weakness and atrophy, with high rates of morbidity and mortality despite recent treatments.
* The study reviewed 16 SMA type 1 patients, noting complications like gastrointestinal issues, respiratory distress, and infections, with a 50% mortality rate during the follow-up period.
* Findings suggest higher survival rates are linked to more nusinersen treatments and better overall health scores, indicating a need for a multidisciplinary approach to patient management.

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The diversity in the clinical features of children hospitalized with COVID-19 during the nonvariant, Alpha (B.1.1.7), Delta (B.1.617.2), and Omicron (B.1.1.529) variant periods of SARS CoV-2: Caution for neurological symptoms in Omicron variant.

Aslıhan Sahin Eda Karadag-Oncel Osman Buyuksen Yildiz Ekemen-Keles Gulnihan Ustundag

J Med Virol

March 2023

Since the COVID-19 pandemic began, various severe acute respiratory syndrome coronavirus 2 variants have been identified with different characteristics than the nonvariant strain. We retrospectively evaluated the demographic and clinical differences in the cohort of hospitalized COVID-19 children (1 month-18 years old) between March 11, 2020, and September 31, 2022, by the time the variants identified in our country predominate. Bonferroni post hoc analysis was performed to compare the differences between the periods.