Biopolymeric film containing bioactive naphthoquinone (shikonin) in combined therapy of inflammatory destructive lesions in the buccal mucosa.

Clinical morphological efficiency of local application of a new biopolymeric film was studied. The film was based on methylcellulose derivatives and contained shikonin (preparation of plant origin) and its esters isolated from Lithospermum erythrorhizon L. cell culture.

Pathomorphological and immunohistochemical analysis of proliferative activity of the buccal mucosal epithelium in lichen planus.

Structural reorganization of the buccal mucosa and changes in proliferative activity of epitheliocytes in typical and erosive ulcerative lichen planus were studied. The most manifest diagnostically significant pathomorphological signs of lichen planus of the buccal mucosa are described: acanthosis, granulosis, parakeratosis, lymphocytic infiltration of the lamina propria, and edema. The most pronounced morphological changes and higher index of epitheliocyte proliferative activity (by expression of Ki-67) are characteristic of the erosive ulcerative form of the disease.

[Prevalence of secondary deformities of dentition and diseases of temporomandibular joint in the population of Far East].

Epidemiological survey of 1161 indigenous people (I group) and 1000 people came (II group) of the population of Far East in the age over than 20 years was conducted. Established that the deformation of dentitions at diagnosis was found in 22.13% I group, 20.

Morphological and immunological analysis of the oral mucosa in tobacco smoking and odontopreparation.

Tobacco smoking causes pronounced structural reorganization of the gingival mucosa and its atrophic changes. Odontopreparation stimulates destructive processes in the gingival mucosa promoting activation of local immunity (stimulation of immunoglobulin synthesis). Significant differences in the local humoral immunity (IgG dysimmunoglobulinemia) and cytokine spectrum in nonsmoking and tobacco-smoking patients were detected.

[The characteristics of proliferative processes in the epithelium of human gingival mucosa (an autoradiographic study)].

Autoradiographic examinations of gingival mucosa biopsy specimens obtained from 117 subjects aged 17 to 78 have demonstrated a higher intensity of the proliferation processes in females as against men. No age-specific differences in the proliferation parameters were revealed. These data may be useful in studies of the possible disorders of the proliferative processes in various abnormalities of the buccal mucosa.

[The morphometric characteristics of the masticatory muscle of dogs with an expanded interalveolar space].

The experiment with 24 dogs involved increase of their interalveolar space in the frontal section by 6 mm via fixation of metal crowns on 98 189 teeth. Follow-up of the masticatory muscle adaptation has shown that it ran a wave-like course. The most intensive shifts are observed on days 7-14 of the experiment, this being followed by a gradual recovery of this muscle tinctorial characteristics by the 20th day of the experiment; then the restructuring process stabilizes on a new structural and functional level by days 30-60 of the experiment.