PSA quo vadis? It is reasonable to start with prostate-specific antigen testing at the age of 40!

Background: It is common to start with PSA (prostate-specific antigen)-testing at the age of 50. If patients with a PSA value greater than 4 ng/mL should be considered for prostate biopsy, approximately 20% of all men undergoing test are considered for biopsy at the time of first early-detection examination.

Methods: We have screened 2,592 asymptomatic men younger than 45 years.