The use of combined high-fructose diet and glyphosate to model rats type 2 diabetes symptomatology.

An ideal food-chemical combination that will promote insulin resistance and its consequent development of pancreatic beta-cell dysfunction may open a new vista for Type 2 diabetes (T2D) research. Thus, we investigated the modulatory effects of a high-fructose diet (FRC) combined with glyphosate (GP). Male albino Wistar rats were randomly divided into five groups of eight/group and received distilled water, FRC, GP, and their combinations orally for eight consecutive weeks.

Chemoprotective effects of butanol fraction (Capparidaceae) against type 2 diabetes and oxidative stress in male Wistar rats.

Recent studies have shown that Type 2 diabetes (T2D) in rats can result through a synergy that links obesity to insulin resistance and β-cell dysfunction. The present study achieved T2D via high fructose (20%, p.o.

Aqueous fraction of Alstonia boonei de Wild leaves suppressed inflammatory responses in carrageenan and formaldehyde induced arthritic rats.

Alstonia boonie de Wild is an ethnomedical plant used as therapy against inflammatory disorders. This study evaluated the most active anti-inflammatory and anti-oxidant fraction of A. boonei leaves using in vitro and in vivo models.

Hematological and lipid profile evaluation of a hexane fraction of Costus afer leaves in arthritic rats.

Context: Costus afer Ker Gawl. (Costaceae) is an ethnomedical plant used as therapy against inflammatory disorders.

Objective: The objective of this study was to evaluate the hematological and lipid profile analysis of hexane fraction of C.

Proximate composition, mineral content and in vitro antioxidant activity of leaf and stem of Costus afer (Ginger lily).

Aim: This study was designed to determine the proximate composition and mineral content of Costus afer leaf and stem, as well as to identify the most active antioxidant fraction.

Materials And Methods: The proximate composition and mineral analysis of C. afer leaf and stem were performed using the standard methods described by Pearson and Association of Official Analytical Chemist while the 1,1 diphenyl 2 picryl hydrazyl (DPPH), thiobarbituric acid reactive species (TBARS), lipid peroxidation (LPO), and total antioxidant capacity (TAC) assays were used to determine the in vitro antioxidant activity of aqueous, n-butanol, ethyl acetate and hexane fractions of C.

Anti-inflammatory and antioxidant activities of Costus afer Ker Gawl. hexane leaf fraction in arthritic rat models.

Ethnopharmacological Relevance: Costus afer Ker Gawl is an indigenous tropical African medicinal plant used as therapy in the treatment of inflammatory ailments such as rheumatoid arthritis. This study was designed to evaluate the anti-inflammatory and antioxidant activities of the hexane fraction of C. afer leaves (CAHLF).

Fruits and vegetables diet improves some selected haemorheological parameters predisposing to cardiovascular disease in non insulin dependent diabetes mellitus NIDDM subjects.

Fruits and vegetables have been shown to contain vital components that moderate disease conditions. However, there is dearth of information of these effects in Africans diabetic subjects. Thus, we investigated the relative effect of fruits and vegetables on some selected heamorological factors associated with cardiovascular disease in diabetic subjects.

Fruits and vegetables moderate lipid cardiovascular risk factor in hypertensive patients.

Hyperlipidemia is a major risk factor in etiology of cardiovascular disease. Previous studies have shown association between vegetarian diet and low total serum cholesterol as well as LDL-cholesterol which is a pointer to low risk of cardiovascular disease. Dietary fiber, antioxidants and other classes of nutrients have been reported to ameliorate cardiovascular risk factors.

The influence of a vegetarian diet on haemostatic risk factors for cardiovascular disease in Africans.

Dietary habits have been implicated in the occurrence of cardiovascular diseases. Elevated plasma fibrinogen levels and decreased fibrinolytic activity have been identified as major independent cardiovascular risk factors. In this study, we compared the blood pressure, plasma fibrinogen concentration, and fibrinolytic activity of 40 nonvegetarians (NON-VEGs) with 36 vegetarians (8 VEGs and 28 SEMI-VEGs).

Blood pressure and blood lipid levels among vegetarian, semi-vegetarian, and non-vegetarian native Africans.

Background: Several epidemiological studies have implicated hypercholesterolemia and hypertriglyceridaemia as a dietary risk factor in the etiology of vascular disease. To date, there are virtually no blood lipid data available for Negroid Black African Seventh-Day Adventist vegetarians. This study was undertaken to gain a preliminary and better understanding of the relationships between BP, blood lipids, and diets in adults at the Seventh-Day Adventist Seminary of West Africa, Ilisan-Remo, Nigeria.

Prediction of glycemic index for starchy foods.

Associations between published values for glycemic index (GI) and chemical components were examined by regression analysis in 18 starchy foods. Independent variables were the amounts of protein, fat, phytic acid, and total dietary fiber (TDF) present in food portions containing 50 g available carbohydrate. GI was similarly and significantly correlated (P < 0.

Hepatic responses to edible gums during refeeding of starved rats.

The ability of edible gums to depress total liver lipids and activities of two hepatic enzymes (glucose-6-phosphate dehydrogenase and NADP-linked malic enzyme) was examined during the refeeding of 2 d starved rats. Gums were fed as 4% of dry ingredients, occasionally with added water, in otherwise identical high glucose, nutritionally adequate diets. Feeding of xantham gum for 1 or 2 d decreased the rise in two enzyme activities and in total liver lipids, but after 4 or 7 d only total liver lipids were affected.

Use of xanthan gum in dietary management of diabetes mellitus.

Xanthan gum (12 g/day) was fed in muffins during either the first or second half of a 12-wk period of muffin feeding, to free-living subjects. Nine subjects were diabetic, having moderately elevated serum glucose but managing without insulin or hypoglycemic drugs, and four were nondiabetic controls. Before the study and at the end of the xanthan and xanthan-free periods, bloods were taken before and 2 h after an oral glucose load.

Effects of fructose feeding on lipid parameters in obese and lean, diabetic and nondiabetic Zucker rats.

Effects of fructose feeding in moderate amounts on lipid metabolism of obese versus lean, and diabetic versus nondiabetic Zucker rats, were studied. Forty pairs of male lean and obese animals were assigned to two dietary groups, fructose and glucose. For each diet, one-half of lean and obese animals were injected with streptozotocin intraperitoneally (i.