Publications by authors named "Oshima Jain"
Background The objective of this study was to investigate the association of polymorphisms in four genes, tumor necrosis factor-α (TNFA), patatin-like phospholipase domain containing 3 (PNPLA3), adiponectin (ADIPOQ) and apolipoprotein C3 (APOC3), with obesity and non-alcoholic fatty liver disease (NAFLD) in Asian Indian adolescents. Methods In this case-control study, 218 Asian Indian adolescents with overweight/obesity and 86 lean healthy adults without fatty liver were enrolled. Hepatic steatosis was assessed and graded by ultrasonography (USG).
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- - The study aimed to evaluate the prevalence of non-alcoholic fatty liver disease (NAFLD) in overweight Indian adolescents and its relationship with various clinical and biochemical factors.
- - Out of 218 adolescents aged 10-16, 62.5% were diagnosed with NAFLD, with significant differences in body fat, blood pressure, and liver enzymes between those with and without the condition.
- - Factors such as abdominal obesity and insulin resistance were found to be independently linked to NAFLD, highlighting the need for awareness and management of these risk factors in overweight youth.