Bullet embolism is a rare but potentially serious complication of a gunshot wound. This case report describes a 26-year-old male who presented with a gunshot to the lower back. Diagnostics revealed a migrating bullet that became lodged in the left pulmonary artery.
View Article and Find Full Text PDFBackground: Flavonoids have been shown to exert anti-pathogenic potential, but few studies have investigated their effects on () infectivity. We hypothesized that a flavonoid mixture would have a favorable influence on cell death and the resolution of infection in THP-1 macrophages and in granulomas derived from both healthy participants and those with type 2 diabetes mellitus (T2DM).
Methods: THP-1 macrophages, and in vitro granulomas from healthy participants ( = 8) and individuals with T2DM ( = 5) were infected with .
Glutathione (GSH), often referred to as "the master antioxidant," participates not only in antioxidant defense systems, but many metabolic processes, and therefore its role cannot be overstated. GSH deficiency causes cellular risk for oxidative damage and thus as expected, GSH imbalance is observed in a wide range of pathological conditions including tuberculosis (TB), HIV, diabetes, cancer, and aging. Consequently, it is not surprising that GSH has attracted the attention of biological researchers and pharmacologists alike as a possible target for medical intervention.
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