In-Silico Selection of Wound-Healing Plant Secondary Molecules and Their Pro-Healing Activities on Experimental Models.

This study explored the potential of plant-derived molecules (PDMs) as a medicinal treatment for skin wounds. To assess their healing properties, 34 potential drug molecules (PDMs) and ten therapeutic targets were subjected to molecular docking and dynamics analysis, with allantoin used as a standard compound. Although aristolochic acid had the most potent inhibitory effect, its toxicity made it unsuitable for testing on cells and mice.

Green Bank and Effelsberg Radio Telescope Searches for Axion Dark Matter Conversion in Neutron Star Magnetospheres.

Axion dark matter (DM) may convert to radio-frequency electromagnetic radiation in the strong magnetic fields around neutron stars. The radio signature of such a process would be an ultranarrow spectral peak at a frequency determined by the mass of the axion particle. We analyze data we collected from the Robert C.

Conus Medullaris Level in Vertebral Columns With Lumbosacral Transitional Vertebra.

Background: The estimated prevalence of lumbar or sacral transitional vertebrae (LSTV) in the population is 4% to 30%. Few small patient series have studied the normal level of the conus medullaris (CM) in individuals with LSTV.

Objective: To determine, by using a large cohort of patients, whether individuals of all ages with LSTV have different CM positions in the spinal canal in comparison with the rest of the population with normal vertebral columns.

HIV treatment cascade among transgender women in a San Francisco respondent driven sampling study.

Objective: Male-to-female transgender women (transwomen) have a disproportionate burden of HIV. We sought to estimate HIV treatment cascade indicators among transwomen in San Francisco.

Methods: We conducted a respondent driven sampling (RDS) study of 314 transwomen from August to December 2010.

Alcohol and substance use among transgender women in San Francisco: prevalence and association with human immunodeficiency virus infection.

Introduction And Aims: Alcohol and substance use can have negative health consequences among both human immunodeficiency virus (HIV)-positive and -negative individuals, and are associated with behaviors that facilitate HIV transmission and acquisition. The relationship of substance use and HIV is well documented among key populations at risk for HIV. However, although transwomen (male-to-female transgender) are disproportionately impacted by HIV, this overlap remains understudied in this population.