Association between donor-specific antibodies and acute rejection and resolution in small bowel and multivisceral transplantation.

Background: Donor-specific antibodies (DSA) are associated with acute kidney graft rejection, but their role in small bowel/multivisceral allograft remains unclear. We carried out a prospective study to understand the impact of DSA in the setting of intestinal allograft rejection.

Methods: Thirteen patients (15 grafts) were serially evaluated for DSA levels pre- and posttransplant.

Stem cells: a primer.

Having great therapeutic and biotechnological potential, stem cells are extending the frontier in medicine. Not only replace dysfunctional or damaged cells, the so-called regenerative medicine, stem cells may also offer us new perspectives regarding the nature of aging and cancer. This review will cover some basics of stem cells, their current development, and possible applications in medicine.