Bioactive Compounds from That Regulate QS, Biofilm Formation and Virulence Factor Production of .

is an opportunistic pathogen responsible for many nosocomial infections. This bacterium uses Quorum Sensing (QS) to generate antimicrobial resistance (AMR) so its disruption is considered a novel approach. The current study describes the antibiofilm and QS inhibitory potential of extract and chemical components from .

Antiquorum and Antibiofilm Activities of C. DC. against and Identification of Bioactive Compounds.

The present study describes the anti-biofilm and quorum sensing (QS) inhibitory potential of extracts and chemical constituents from . Antibiofilm potential was determined through crystal violet assay against , while QS inhibition efficacy was determined through violacein inhibition assay using as a bacterial model. Additionally, this study reports the effects of the chemical constituents isolated in against various virulent factors associated with QS, such as the percentage decrease in pyocyanin, elastase, and protease production.

In Vitro and In Silico Study of the α-Glucosidase and Lipase Inhibitory Activities of Chemical Constituents from (Piperaceae) and Synthetic Analogs.

Digestive enzymes are currently considered important therapeutic targets for the treatment of obesity and some associated metabolic diseases, such as type 2 diabetes. is a species characterized by the presence of bioactive constituents, particularly prenylated benzoic acid derivatives. In this study, the inhibitory potential of chemical constituents from and some synthesized compounds was determined on digestive enzymes (pancreatic lipase (PL) and α-glucosidase (AG)).

Multitarget Action of Xanthones from against α-Amylase, α-Glucosidase and Pancreatic Lipase.

Digestive enzymes such α-amylase (AA), α-glucosidase (AG) and pancreatic lipase (PL), play an important role in the metabolism of carbohydrates and lipids, being attractive therapeutic targets for the treatment of type 2 diabetes and obesity. is an interesting species because there have been identified xanthones with the potential to inhibit these enzymes. In this study, the multitarget inhibitory potential of xanthones from against AA, AG and PL was assessed.

Fumigant toxicity and biochemical effects of selected essential oils toward the red flour beetle, Tribolium castaneum (Coleoptera: Tenebrionidae).

Tribolium castaneum Herbst (Coleoptera: Tenebrionidae) is an insect popularly known as the red flour beetle, it is widely distributed worldwide and can cause serious damage to stored grains. Chemical control is the most used method for managing this pest, however, some substances are toxic to mammals and the environment. Therefore, the development of new effective and safe insecticides is necessary.

Effects of Essential Oils from 24 Plant Species on Motsch (Coleoptera, Curculionidae).

Chemical control of the maize weevil () has been ineffective and presents serious collateral damage. Among plant-derived insecticides, essential oils (EOs) are suitable candidates to control this stored products pest. In this work, the insecticidal activities of 45 natural EOs against adults were screened, and the most promising ones (24 EOs) were characterized by GC-MS.

Antifungal Activity of Chemical Constituents from C. DC. and Derivatives against Phytopathogen Fungi of Cocoa.

In this study, the antifungal potential of chemical constituents from and some synthesized derivatives was determined against three phytopathogenic fungi associated with the cocoa crop. The methodology included the phytochemical study on the aerial part of , the synthesis of some derivatives and the evaluation of the antifungal activity against the fungi , and sp. The chemical study allowed the isolation of three benzoic acid derivatives (-), one dihydrochalcone () and a mixture of sterols (-).

Effect of methyl jasmonate and salicylic acid on the production of metabolites in cell suspensions cultures of (Piperaceae).

Elicitation of cell suspensions culture is a strategy that could increase the production of secondary metabolites under controlled conditions. This research evaluated the effect of methyl jasmonate-MeJA and salicylic acid-SA as elicitors on the production of metabolites in cell suspensions of . The type of elicitor (MeJA or SA), the concentration of elicitor (10 μM and 100 μM), and time of exposition (3, 12, 24 h) on cell suspension were evaluated.