Stressful experiences form stronger memories due to enhanced neural plasticity mechanisms linked to glucocorticoid hormones (cortisol in humans, corticosterone in rats). Among other neural structures, the dorsal striatum plays a role in the corticosterone-induced consolidation of stressful memories, particularly in the cued water maze task. Neural plasticity is related to mitochondrial activity due to the relevance of energy production and signaling mechanisms for functional and morphological neuronal adaptations.
View Article and Find Full Text PDFBackground: Microsurgical and endoscopic approaches are accepted alternatives for the management of symptomatic arachnoid cyst. However, given their ability to visualize critical neurovascular structures with less morbidity, less dissection needs, and high success rates, endoscopic approaches are excellent options for the management of this pathology.
Case Description: We present the case of an otherwise healthy 8-year-old male who presented with a chronic history of disabling headache that augmented with exercise and interrupted his sleep.
This article proposes the application of the maximum-entropy principle (MEP) to agency contracting (where a hires an to make decisions on their behalf) in situations where the principal and agent only have partial knowledge on the probability distribution of the output conditioned on the agent's actions. The paper characterizes the second-best agency contract from a maximum entropy distribution (MED) obtained from applying the MEP to the agency situation consistently with the information available. We show that, with the minimum shared information about the output distribution for the agency relationship to take place, the second-best compensation contract is (a monotone transformation of) an increasing affine function of output.
View Article and Find Full Text PDFBackground: Taxanes adjuvant therapy is recommended in certain high risk or metastatic tumors, particularly in lung and breast cancer, but also in other types of cancer like ovarian. The incidence of severe adverse drug reactions to paclitaxel is of approximately 10%.
Objectives: Analyze type I hypersensitivity reactions to paclitaxel and their management in the Mexican population.
The main objective of the work reported here was the analysis and evaluation of halloysite nanotubes (HNTs) as natural flame retardancy filler in partially biobased polyamide 610 (PA610), with 63% of carbon from natural sources. HNTs are naturally occurring clays with a nanotube-like shape. PA610 compounds containing 10%, 20%, and 30% HNT were obtained in a twin-screw co-rotating extruder.
View Article and Find Full Text PDFIn this article, we present a meta-analysis and a scientific mapping about the relationship between different types of well-being and job performance. We followed The PRISMA statement for reporting systematic reviews and meta-analyses (Moher et al., 2009), and conduct the search in Web of Science, SCOPUS, Ebscohost, Proquest, and Jstor databases.
View Article and Find Full Text PDFBMC Med Genet
September 2020
Background: Adiponectin gene (ADIPOQ) polymorphisms have been shown to affect adiponectin serum concentration and some have been associated with breast cancer (BC) risk. The aims of this study were to describe the frequency of single nucleotide polymorphisms (SNPs) of ADIPOQ in Mexican women with BC and to determine if they show an association with it.
Methods: DNA samples from 397 patients and 355 controls were tested for the ADIPOQ gene SNPs: rs2241766 (GT) and rs1501299 (GT) by TaqMan allelic discrimination assay.
This work shows a patent database for that provides an overview of the patenting activity and trends in focused antiviral therapy with the use of triazole based compounds, glycoprotein, and protease inhibitors as possible treatment. The patent data was obtained from Orbit Intelligence Software using a patent family structure to get a big database that could be used for built patent landscape report (PLR), market analysis, technical and competitive intelligence, and monitoring and survey of a new ideas for the treatment of coronavirus diseases. The raw data is reported in four databases, which were classified according to different items: legal status (alive, dead), 1 application year (after 2015, 2011-2015, 2006-2010, 2001-2005), and Top 5 International Patents Classifications (IPC).
View Article and Find Full Text PDFTraumatic brain injury (TBI) is a global public health problem. In Colombia, it is estimated that 70% of deaths from violence and 90% of deaths from road traffic accidents are TBI related. In the year 2014, the Ministry of Health of Colombia funded the development of a clinical practice guideline (CPG) for the diagnosis and treatment of adult patients with severe TBI.
View Article and Find Full Text PDFWe modeled the experimentally observed self-assembly of nanoparticles (NPs) into shells with diameters up to 10 μm, via segregation from growing nematic domains. Using field-based Monte Carlo simulations, we found the equilibrium configurations of the system by minimizing a free-energy functional that includes effects of excluded-volume interactions among NPs, orientational elasticity, and the isotropic-nematic phase-transition energy. We developed a Gaussian-profile approximation for the liquid crystal (LC) order-parameter field that provides accurate analytical values for the free energy of LC droplets and the associated microshells.
View Article and Find Full Text PDFThis study aimed at exploring whether 3D technology enhances tennis decision-making under the conceptual framework of human performance model. A 3 (skill-level: varsity, club, recreational) × 3 (experimental condition: placebo, weak 3D [W3D], strong 3D [S3D]) between-participant design was used. Allocated to experimental conditions by a skill-level stratified randomization, 105 tennis players judged tennis serve direction from video scenarios and rated their perceptions of enjoyment, flow, and presence during task performance.
View Article and Find Full Text PDFThe genus Borrelia includes species responsible for severe human diseases such as Lyme disease. Birds are involved in their epidemiology as dispersers of infected ticks (Ixodida: Ixodidae) and as reservoirs or amplifiers of the bacterium. Herein, the presence of Borrelia burgdorferi sensu lato (s.
View Article and Find Full Text PDFCrimean-Congo hemorrhagic fever virus (CCHFV) was detected in Spain in 2010. The presence of CCHFV in Hyalomma marginatum ticks from migratory birds passing through Morocco during the spring migration strengthened the hypothesis of the arrival of infected ticks transported by birds to the Iberian Peninsula. Furthermore, Hyalomma species are vectors of bacterial infections such as spotted fever rickettsioses.
View Article and Find Full Text PDFWe study electromagnetic field propagation through a planar three-waveguide coupler with linear gain or loss in a configuration that is the optical analog of a quantum PT-symmetric system. This model is experimentally feasible on at least four proven architectures: lossy waveguide couplers, pumped waveguides couplers, non-Hermitian electronics and coupled pumped whispering gallery mode resonators. We show that our device provides all-optical amplitude (phase) to phase (amplitude) conversion in the PT-symmetric regime at given propagation lenghts.
View Article and Find Full Text PDFThe execution variability and outcomes found in throwing actions have received special attention in numerous studies in recent years. The aim of this study was to analyze the effect of an unstable condition on velocity, accuracy and kinematics of movement in the seven metres throw in handball. Twenty-five young handball players took part in an experiment, throwing towards a target on a stable and an unstable surface.
View Article and Find Full Text PDFThis article assesses the game performance of the teams participating in the Men's World Championship of Handball of 2011 by using Data Envelopment Analysis (DEA) and the cross-efficiency evaluation. DEA uses Linear Programming to yield a measure of the overall performance of the game of particular teams, and allows us to identify relative strengths and weaknesses by means of benchmarking analysis. The cross-efficiency evaluation provides a peer-appraisal of the teams with different patterns of game, and makes it possible to rank them.
View Article and Find Full Text PDFCrimean-Congo hemorrhagic fever virus was detected in ticks removed from migratory birds in Morocco. This finding demonstrates the circulation of this virus in northwestern Africa and supports the hypothesis that the virus can be introduced into Europe by infected ticks transported from Africa by migratory birds.
View Article and Find Full Text PDFPseudomonas pseudoalcaligenes CECT5344 is a Gram-negative bacterium able to tolerate cyanide and to use it as the sole nitrogen source. We report here the first draft of the whole genome sequence of a P. pseudoalcaligenes strain that assimilates cyanide.
View Article and Find Full Text PDFAlthough computers and information technology (IT) have penetrated the field of social work, little research has systematically studied how users respond to this infusion. Information systems researchers have accumulated significant insights into IT acceptance in business organizations after decades of efforts. In this study, users in the social services were assessed for their acceptance of IT.
View Article and Find Full Text PDFThe acute and subacute toxicity of the aqueous extract of Salvia scutellarioides (Lamiaceae) was studied in mice and rats. In the acute toxicity test, oral administration of 2g/kg of Salvia scutellarioides produced neither mortality nor changes in behavior or any other physiological activities. In subacute toxicity studies, no mortality was observed when the two doses of 1 or 2g/kgday of aqueous extract of Salvia scutellarioides extract were administered orally for a period of 28 days.
View Article and Find Full Text PDFIntroduction: In the Colombian traditional medicine, an infusion made of the entire plant Salvia scutellarioides (known locally as mastranto or oreja de perro (dog's ear)) is used for its antihypertensive and diuretic effects. However, experimental studies have never been done to validate the reported effects.
Objective: In the current study, a rat model was used to determine the effect of S.
Low-level laser-assisted liposuction (LLLL), known as the Neira 4 L technique, is an excellent adjuvant tool for the surgeon practicing liposculpture. A low-level laser is used to create a transitory pore in the cell membrane of the adipocyte to move fat from inside the cell to the interstitial space outside without killing the cell. LLLL has been performed successfully in in-vitro and human adipose tissue cultures.
View Article and Find Full Text PDFThis study searched for mutations in the MLH1 and MSH2 genes in 23 unrelated Colombian families with suspected hereditary nonpolyposis colorectal cancer (HNPCC). The families were grouped according to the fulfillment of the Amsterdam II criteria or the Bethesda guidelines. We screened all probands by single-strand conformational polymorphism (SSCP) and direct DNA sequencing.
View Article and Find Full Text PDFIntroduction: Colorectal cancer (CRC) is the second highest cause of cancer mortality in developed countries. In Colombia, CRC ranks fifth as a cause of cancer death. Approximately 75% of CRC appear to be spontaneous and 25% are familial, with 5% of the latter clearly hereditary.
View Article and Find Full Text PDFPCR for vacA and cagA genotypes of Helicobacter pylori using DNA isolated from infected gastric biopsy specimens was approximately equal to genotyping using bacterial DNA from cultures. Inconsistent results were associated with low H. pylori density in biopsies.
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