Publications by authors named "Oscar Garcia-Valencia"

Background: Pancreas transplantation, a crucial treatment for diabetes, is underutilized due to its invasiveness, strict criteria, organ scarcity, and limited centers. This highlights the need for enhanced public education and awareness through digital health platforms.

Methods: We utilized Google's AI-driven, consensus-based model and Claude AI 3.

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  • The 2024 Nephrology fellowship match data reveals a 11% decline in candidates with only 66% of positions filled, signaling decreasing interest in this specialty compared to other internal medicine fields.
  • A study using ChatGPT analyzed nephrology against 13 other specialties, scoring it low on work-life balance, patient relationships, and career demand, ranking it just above sleep medicine.
  • The findings indicate nephrology's declining appeal, raising concerns about potential physician shortages and prompting a need to investigate what factors are influencing medical residents' specialty choices.
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  • - The study evaluated the safety and effectiveness of semaglutide, a diabetes and weight loss medication, in patients with advanced chronic kidney disease (CKD) stages 4 and 5, as well as those on dialysis, due to limited existing research in this area.
  • - Data from 76 patients (mostly males with a mean age of 66.8) was analyzed over approximately five years, showing significant weight loss (avg. drop of 4.9 kg) and decreased hemoglobin A1c levels (avg. drop from 8.0% to 7.1%).
  • - While 63.1% reported no adverse effects, the most common issues leading to discontinuation were nausea, vomiting,
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Background: Pancreas transplantation is a crucial surgical intervention for managing diabetes, but it faces challenges such as its invasive nature, stringent patient selection criteria, organ scarcity, and centralized expertise. Despite the steadily increasing number of pancreas transplants in the United States, there is a need to understand global trends in interest to increase awareness of and participation in pancreas and islet cell transplantation.

Methods: We analyzed Google Search trends for "Pancreas Transplantation" and "Islet Cell Transplantation" from 2004 to 14 November 2023, assessing variations in search interest over time and across geographical locations.

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  • - This study explored how well ChatGPT, an advanced AI, can simplify living kidney donation information to make it easier for people who read at an 8th-grade level or below, which is crucial given the average American adult's reading ability.
  • - ChatGPT 3.5 and 4.0 successfully lowered the readability of complex FAQs from an average grade level of 9.6 to 7.72 and 4.30 respectively, with ChatGPT 4.0 outperforming the earlier version in making nearly all content accessible below an 8th-grade level.
  • - The results highlight ChatGPT's potential to improve access to important medical information, promoting diversity and equity in living kidney donation, while suggesting further
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Health equity and accessing Spanish kidney transplant information continues being a substantial challenge facing the Hispanic community. This study evaluated ChatGPT's capabilities in translating 54 English kidney transplant frequently asked questions (FAQs) into Spanish using two versions of the AI model, GPT-3.5 and GPT-4.

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In the aftermath of the COVID-19 pandemic, the ongoing necessity for preventive measures such as mask-wearing and vaccination remains particularly critical for organ transplant recipients, a group highly susceptible to infections due to immunosuppressive therapy. Given that many individuals nowadays increasingly utilize Artificial Intelligence (AI), understanding AI perspectives is important. Thus, this study utilizes AI, specifically ChatGPT 4.

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  • * A major challenge is the potential for LLMs to produce inaccuracies or "hallucinations," which is critical in medical settings where precision is vital.
  • * Strategies like prompt engineering and retrieval-augmented generation (RAG) have been developed to improve accuracy, with the article highlighting a specialized ChatGPT model that aligns with current chronic kidney disease guidelines for better medical advice.
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Accurate information regarding oxalate levels in foods is essential for managing patients with hyperoxaluria, oxalate nephropathy, or those susceptible to calcium oxalate stones. This study aimed to assess the reliability of chatbots in categorizing foods based on their oxalate content. We assessed the accuracy of ChatGPT-3.

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The emergence of artificial intelligence (AI) has greatly propelled progress across various sectors including the field of nephrology academia. However, this advancement has also given rise to ethical challenges, notably in scholarly writing. AI's capacity to automate labor-intensive tasks like literature reviews and data analysis has created opportunities for unethical practices, with scholars incorporating AI-generated text into their manuscripts, potentially undermining academic integrity.

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The rapid advancement of artificial intelligence (AI) technologies, particularly machine learning, has brought substantial progress to the field of nephrology, enabling significant improvements in the management of kidney diseases. ChatGPT, a revolutionary language model developed by OpenAI, is a versatile AI model designed to engage in meaningful and informative conversations. Its applications in healthcare have been notable, with demonstrated proficiency in various medical knowledge assessments.

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Background: Educational attainment significantly influences post-transplant outcomes in kidney transplant patients. However, research on specific attributes of lower-educated subgroups remains underexplored. This study utilized unsupervised machine learning to segment kidney transplant recipients based on education, further analyzing the relationship between these segments and post-transplant results.

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  • * Four AI models—ChatGPT 3.5, ChatGPT 4, Bard AI, and Bing Chat—were tested for their abilities to classify the potassium and phosphorus content of 240 CKD-friendly food items.
  • * ChatGPT 4 was the most effective for potassium identification, with an 81% accuracy rate, while Bard AI excelled at phosphorus classification, achieving a perfect score; these results highlight the varying effectiveness of AI in supporting dietary management for CKD patients.
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Background: ChatGPT is a novel tool that allows people to engage in conversations with an advanced machine learning model. ChatGPT's performance in the US Medical Licensing Examination is comparable with a successful candidate's performance. However, its performance in the nephrology field remains undetermined.

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This comprehensive critical review critically examines the ethical implications associated with integrating chatbots into nephrology, aiming to identify concerns, propose policies, and offer potential solutions. Acknowledging the transformative potential of chatbots in healthcare, responsible implementation guided by ethical considerations is of the utmost importance. The review underscores the significance of establishing robust guidelines for data collection, storage, and sharing to safeguard privacy and ensure data security.

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Kidney transplantation is a critical treatment option for end-stage kidney disease patients, offering improved quality of life and increased survival rates. However, the complexities of kidney transplant care necessitate continuous advancements in decision making, patient communication, and operational efficiency. This article explores the potential integration of a sophisticated chatbot, an AI-powered conversational agent, to enhance kidney transplant practice and potentially improve patient outcomes.

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Literature reviews are valuable for summarizing and evaluating the available evidence in various medical fields, including nephrology. However, identifying and exploring the potential sources requires focus and time devoted to literature searching for clinicians and researchers. ChatGPT is a novel artificial intelligence (AI) large language model (LLM) renowned for its exceptional ability to generate human-like responses across various tasks.

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Background And Aims: Randomized clinical trials have proven the efficacy and safety of Food and Drug Administration (FDA) approved anti-obesity medications (AOMs) for long-term use. It is unclear whether these outcomes can be replicated in real-world clinical practice where clinical complexities arise. The aim of this study was to evaluate the effectiveness and side effects of these medications in real-world multidisciplinary clinical practice settings.

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Introduction: Lactic acidosis (LA) can be categorized as type A, which occurs in the presence of tissue hypoxia, or type B, occurring in the absence of tissue hypoxia. Hematologic malignancies are an uncommon cause of type B LA.

Case Presentation: A 63-year-old man, HIV-negative, with a history of diabetes mellitus, hypothyroidism, and non-alcoholic fatty liver disease (NAFLD), presented to the ED complaining of acute-on-chronic lumbar pain, and was found to have high serum anion gap (AG) LA.

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Preeclampsia is a pregnancy-specific hypertensive disorder characterized by proteinuria, and vascular injury in the second half of pregnancy. We hypothesized that endothelium-dependent vascular dysfunction is present in a murine model of preeclampsia based on administration of human preeclamptic sera to interleukin-10-/- mice and studied mechanisms that underlie vascular injury. Pregnant wild type and IL-10-/- mice were injected with either normotensive or severe preeclamptic patient sera (sPE) during gestation.

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Background: Hypertensive disorders of pregnancy (HDP) are associated with increased risks for cardiovascular disease later in life. The HDP incidence is commonly assessed using diagnostic codes, which are not reliable; and typically are expressed per-pregnancy, which may underestimate the number of women with an HDP history after their reproductive years.

Objectives: This study sought to determine the incidence of HDP expressed as both per-pregnancy and per-woman, and to establish their associations with future chronic conditions and multimorbidity, a measure of accelerated aging, in a population-based cohort study.

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Reports highlighting the problems with the standard practice of using bar graphs to show continuous data have prompted many journals to adopt new visualization policies. These policies encourage authors to avoid bar graphs and use graphics that show the data distribution; however, they provide little guidance on how to effectively display data. We conducted a systematic review of studies published in top peripheral vascular disease journals to determine what types of figures are used, and to assess the prevalence of suboptimal data visualization practices.

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Objective: To describe the anorectal manometry results in the pediatric population with chronic constipation and acquired anorectal disease.

Materials And Methods: We reviewed the records of children who were referred to the Motility and Pelvic Floor Laboratory of the Hospital San Jose Tecnologico de Monterrey between 2004-2016 for further evaluation with anorectal manometry and who presented acquired anorectal disease.

Results: We reviewed 170 records.

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Background The endothelial glycocalyx is a vasoprotective barrier between the blood and endothelium. We hypothesized that glycocalyx degradation is present in preeclampsia, a pregnancy-specific hypertensive disorder characterized by endothelial dysfunction and activation. Methods and Results We examined the sublingual glycocalyx noninvasively using sidestream dark field imaging in the third trimester among women with normotensive pregnancies (n=73), early (n=14) or late (n=29) onset preeclampsia, or gestational diabetes mellitus (n=21).

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