Cryosurgery of Periocular Moderately Aggressive Basal Cell Carcinoma.

Uncertainty exists regarding the results of treating basal cell carcinomas with a more aggressive growth pattern than nodular growth with cryosurgery. Over the years, some medium aggressive, well-defined basal cell carcinomas have been treated with cryosurgery at the combined ophthalmology-dermatology recipiency at Sahlgrenska University Hospital, Gothenburg in Sweden. The medical records of these patients were reviewed to analyse the results.

Experimental Disc Herniation in the Rat Causes Downregulation of Serotonin Receptor 2c in a TNF-dependent Manner.

Background: During recent decades, the knowledge of the pathophysiology of disc herniation and sciatica has drastically improved. What previously was considered a strict biomechanical process is now considered a more complex interaction between leaked nucleus pulposus and the tissue in the spinal canal. An inflammatory reaction, with tumor necrosis factor (TNF) playing an essential role, has been demonstrated.

New, clinically more relevant model for nerve root injury in the rat.

Study Design: Exposure to nucleus pulposus and displacement of intraspinal nervous structures with assessment of spontaneous behavioral changes in rats.

Objective: To develop a controlled, experimental model for nerve root injury.

Summary Of Background Data: There are a number of experimental models presented for studies on radiculopathies.