Synopsis of recent research by authors named "Oscar Barrios"
- Oscar Barrios' recent research focuses on the development of novel metal complexes, particularly ruthenium(II) complexes containing PEGylated N-heterocyclic carbene ligands, aimed at enhancing biocompatibility and stability for potential applications in cancer therapy.
- His study examines the electronic properties and solubility of these metal complexes in various solvents, demonstrating that modifications in ligand structure, such as the substitution of Cl atoms, can significantly improve stability in aqueous environments.
- Additionally, Barrios investigates the impacts of second-generation carbosilan dendrimers on the HIF-1α/VEGF signaling pathway and their role in disrupting the cell cycle, providing insights into improved therapeutic strategies against aggressive forms of prostate cancer that exhibit hormone resistance.
