Publications by authors named "Oscar A Fernandez Garcia"

Article Synopsis
  • - A study in Alberta from 2022-2023 highlighted cases of Bartonella quintana infection transmitted through solid organ transplants (SOT) from unhoused deceased donors (UDDs), with a notable attack rate of 12.5% among recipients.
  • - Out of 32 organ recipients from seropositive donors, 6 developed skin-related symptoms of bartonellosis, with the majority showing positive serology results for Bartonella.
  • - This incident underscores the risk of unexpected infections from donors with a history of substance use, emphasizing the need for vigilance among clinicians regarding potential transmission through organ transplants.
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Background: Cytomegalovirus (CMV) mismatched, donor IgG-positive/recipient IgG-negative, solid organ transplant recipients (SOTRs) are at high risk of CMV invasive disease. Post-prophylaxis disease is an issue in this population. Some programs employ surveillance after prophylaxis (SAP) to limit the incidence of post-prophylaxis disease.

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Background: The Global increase in colonization by multidrug-resistant (MDR) bacteria poses a significant concern. The precise impact of MDR colonization in solid organ transplant recipients (SOTR) remains not well established.

Objectives: To assess the impact of MDR colonization on SOTR's mortality, infection, or graft loss.

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The increased procurement of organs from donors with risk factors for blood-borne diseases and the expanding syphilis epidemic have resulted in a growing number of organs transplanted from donors with reactive syphilis serology in our center. Based on guidelines, recipients typically receive therapy shortly after the transplant, but data on outcomes are limited. The primary objective of this study was to determine syphilis seroconversion rates at three months post-transplant in recipients of solid organs procured from donors with reactive syphilis serology.

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Background: In the absence of an adequate prevention strategy, up to 20% of CMV IgG+ liver transplant recipients (LTR) will develop CMV disease. Despite improved reporting in CMV-DNAemia, there is no consensus as to what the ideal CMV-DNAemia cutoff for a successful preemptive strategy is. Each transplant centre establishes their own threshold.

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Emergency department areas were repurposed as intensive care units (ICUs) for patients with acute respiratory distress syndrome during the initial months of the coronavirus disease 2019 (COVID-19) pandemic. We describe an outbreak of New Delhi metallo-β-lactamase 1 (NDM-1)-producing Escherichia coli infections in critically ill COVID-19 patients admitted to one of the repurposed units. Seven patients developed infections (6 ventilator-associated pneumonia [VAP] and 1 urinary tract infection [UTI]) due to carbapenem-resistant E.

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Article Synopsis
  • * The innate immune system, which includes elements like epithelial cells and phagocytes, plays a crucial role in detecting and eliminating fungi while also triggering the adaptive immune response.
  • * The review discusses the differences in immune responses to mucocutaneous versus invasive fungal diseases and examines specific signaling pathways involved in these processes, particularly through insights gained from studying genetic immunity disorders.
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Background: Regional information regarding the characteristics of patients with coronavirus disease (COVID)-19 is needed for a better understanding of the pandemic.

Objective: The objective of the study to describe the clinical features of COVID-19 patients diagnosed in a tertiary-care center in Mexico City and to assess differences according to the treatment setting (ambulatory vs. hospital) and to the need of intensive care (IC).

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