Publications by authors named "Osamu Kikumoto"
Brain Commun
October 2023
Article Synopsis
- Pontine autosomal dominant microangiopathy and leukoencephalopathy is a hereditary condition linked to small vessel diseases affecting the brain, marked by small infarctions in the pons region.
- Researchers conducted genetic sequencing and clinical assessments on a family with this undiagnosed condition and identified a specific genetic variant that confirmed the diagnosis in two other patients.
- A notable radiological feature termed the "raisin bread sign" was discovered, characterized by multiple oval small infarctions in the pons, which corresponds with specific pathological changes observed postmortem.
