Background: Early detection of metastasis and recurrence of Ewing sarcoma (ES) is important for early management. This work aimed to detect CD99 , CD45 cells in peripheral blood by flow cytometry (FC) before and during chemotherapy and evaluate their prognostic significance.
Procedure: This prospective cohort study was carried out on 60 children newly diagnosed with ES at Children Cancer Hospital-Egypt 57357 and 40 healthy children control group.