Ewing Sarcoma of the Scapula: A Rare Case of a 10-Year-Old Child With a Two-Year Follow-Up.

Ewing sarcoma is a very common type of malignant bone tumor among children and adolescents that most frequently develops in long bones of the body and extremities; however, it can also affect other bones such as the skull and scapula in rare cases. In Ewing sarcoma, the most common sites of metastasis are the lungs and bones, which indicates a late stage of the disease and is considered a poor prognostic factor. In this paper, we report the case of a 10-year-old boy presenting with a painless swelling on his left shoulder that was not associated with other local or systemic symptoms, and with no neurological manifestations.

Rare Case of Scapular Body Chondrosarcoma Treated With Limb-Salvage Partial Scapulectomy: A Case Report Highlighting Surgical Technique.

Chondrosarcomas are the second most malignant mesenchymal tumors that originate from neoplastic cells producing cartilage. It usually affects different sites in the body, such as the pelvis, humerus, and ribs, and rarely involves the scapula. The main modality of treatment of chondrosarcoma is surgery, while chemotherapy has been shown to be an ineffective treatment, and radiotherapy is only used in high-grade tumors.

Comprehensive Management of Distal Clavicle Ewing's Sarcoma: A Case Highlighting Surgical Resection, Oncologic Challenges, and Rehabilitation Outcomes.

This case report presents an unusual manifestation of Ewing's Sarcoma (EwS) in the distal clavicle of a 32-year-old male. The patient's journey began with an initial misdiagnosis of a shoulder mass as a benign condition, but advanced imaging techniques later uncovered the malignant nature of the lesion. Emphasizing the complexities of managing EwS in atypical locations and in adult patients, this report details the implementation of a neo-adjuvant chemotherapy regimen.

Giant Cell Tumor With Secondary Aneurysmal Bone Cyst in the Left Distal Humerus: A Case Report.

Giant cell tumor (GCT) is a common benign aggressive tumor that mostly occurs in the proximal tibia, distal radius, and distal femur but is rarely seen in the distal region of the humerus. It originally presents between the ages of 30 and 50 with suddenly occurring pain. Treatment is generally curettage adjuvant treatment if necessary and reconstruction if required.

Prevalence of Classical Extraintestinal Manifestations among Inflammatory Bowel Disease Patients in Saudi Arabia: A Single Tertiary Center Experience.

Background: Patients with inflammatory bowel disease (IBD) may also experience extraintestinal manifestations (EIMs), which can affect various organ systems, and their occurrence is based on disease activity.

Objectives: To determine the prevalence of EIMs and their most common types among IBD patients from Saudi Arabia.

Materials And Methods: This retrospective study included all IBD patients aged 14-80 years who visited the Gastroenterology and Hepatology clinics at King Fahad Medical City, Riyadh, between February 2017 and December 2022.

Comparison of Postoperative Pain and Function in Robotic Total Knee Arthroplasty and Conventional Total Knee Arthroplasty Amongst Patients at King Fahad Medical City in Riyadh, Saudi Arabia.

Background Total knee arthroplasty (TKA) is the definitive surgical treatment for end-stage osteoarthritis and has been proven to relieve pain and improve function. With the rise in demand and the number of TKA procedures every year, more studies have been conducted on robotic TKA. Objective The objective of this study is to compare the postoperative pain between robotic and conventional TKA and the postoperative functional level between robotic and conventional TKA.

Feasibility of Percutaneous Image-Guided Combined Treatment of Symptomatic Bone Cyst Using Cryoablation and Bone Graft Substitute.

Purpose: To describe the feasibility and technique of percutaneous image-guided combined treatment of bone cyst (BC) using cryoablation and bone graft substitute injection.

Materials And Methods: Between July 2019 and January 2022, six consecutive patients (ages between 16 and 33 years) with symptomatic BC in pelvic and lower extremity bones underwent percutaneous image-guided combined treatment using cryoablation and bone graft substitute. To induce bone mineralization as early as possible, the cyst cavity was filled with bone graft substitute.

Assessment of Postgraduate Online Medical Education During the COVID-19 Pandemic in Saudi Arabia: A Cross-Sectional Study.

Purpose: The COVID-19 pandemic has limited the traditional way of teaching due to contact restrictions and the trainees being the front-line providers of patient care in certain specialties. During the pandemic, many academic institutes have adopted various methods for utilizing online learning as an alternative to traditional teaching. Numerous studies reported the impact of these changes on medical education with varying results.

Hibernoma of Thigh: A Case Report of 39-Year-Old Male.

Introduction: Hibernoma is an uncommon benign lipomatous tumor that originates from residual brown fat. It commonly affects adult patients aged between 30 and 40 with a slight predominance in male more than female and usually seen in the thigh, shoulder, back, chest, axilla, and neck. The present report aimed to highlight on a viable differential diagnosis of thigh mass including liposarcoma and atypical lipoma.

Epigallocatechin-3-O-gallate modulates global microRNA expression in interleukin-1β-stimulated human osteoarthritis chondrocytes: potential role of EGCG on negative co-regulation of microRNA-140-3p and ADAMTS5.

Purpose: MicroRNAs (miRNAs) are short, non-coding RNAs involved in almost all cellular processes. Epigallocatechin-3-O-gallate (EGCG) is a green tea polyphenol and is known to exert anti-arthritic effects by inhibiting genes associated with osteoarthritis (OA). This study was undertaken to investigate the global effect of EGCG on interleukin-1β (IL-1β)-induced expression of miRNAs in human chondrocytes.

Pediatric aneurysmal bone cyst in the ischial region.

Aneurysmal bone cyst (ABC) is an expanding osteolytic lesion. ABC represents 1% of all primary benign bone tumors, whereby 4-12% occur in the pelvis. The etiology of this disease remains vague.

Integrated Study of Globally Expressed microRNAs in IL-1β-stimulated Human Osteoarthritis Chondrocytes and Osteoarthritis Relevant Genes: A Microarray and Bioinformatics Analysis.

This study was undertaken to identify and characterize the globally expressed microRNAs (miRNAs) involved in interleukin-1β (IL-1β)-induced joint damage and to predict whether miRNAs can regulate the catabolic effects in osteoarthritis (OA) chondrocytes. Out of 1347 miRNAs analyzed by microarrays in IL-1β-stimulated OA chondrocytes, 35 miRNAs were down-regulated, 1 miRNA was up-regulated, and the expression of 1311 miRNAs remained unchanged. Bioinformatics analysis showed the key inflammatory mediators and key molecular pathways are targeted by differentially expressed miRNAs.

Ewing's Sarcoma of Ilium, Presenting as Right Lower Quadrant Pain.

Ewing's sarcoma is a highly malignant tumor of bone and is more common in children in the age group of 10 to 20 years. Sometimes the classic clinical and radiological presentation of Ewing's sarcoma may not be the norm and patient may have an atypical presentation leading to diagnostic confusion. This situation is especially true for Ewing's sarcoma involving iliac bone.