Assessment of Serum Level of Interleukin-37 in Asthmatic Children at Benha University Hospital.

Asthma is a complex inflammatory disease, characterized by airway hyperresponsiveness, inflammation, and reversible airway obstruction. Interleukin-37 (IL-37), functions as a fundamental inhibitor of innate inflammatory and immune responses, and it is an important cytokine in the control of asthma by suppressing the production of inflammatory cytokines. This study aimed to reveal the possible role of IL-37 in asthma through assessment of its serum level in controlled and uncontrolled asthmatic children as compared to controls.