Adverse events in the global healthcare practice of an Occupational Mutual Insurance Company in Spain.

Background: Patient safety is currently a main issue in healthcare practice. Adverse events (AEs) management is a key instrument for the application of strategies to prevent harm to patients.

Objective: To analyze the type, severity and preventability, according to validated scales, of AEs occurring annually in the healthcare practice of an Occupational Mutual Insurance Company in order to implement action plans to improve patient safety.

Costs of a structured early detection program for advanced liver fibrosis and cirrhosis: insights on the "plus" of Check-up 35.

Background: The implementation of an early detection program for liver cirrhosis in a general population has been discussed for some time. Recently, the effectiveness of a structured screening procedure, called SEAL (Structured Early detection of Asymptomatic Liver cirrhosis), using liver function tests (AST and ALT) and APRI to early detect advanced fibrosis and cirrhosis in participants of the German "Check-up 35" was investigated.

Methods: This study identifies the expected diagnostic costs of SEAL in routine care and their drivers and reports on prevailing CLD etiologies in this check-up population.

[COVID-19 and Bipolar Affective Disorder: Subjective Changes in Lifestyle Variables During the First Lockdown During the COVID-19 Pandemic in Austria].

Introduction: The COVID-19 pandemic with its protective measures (e. g. lockdown) had far-reaching effects on everyone's well-being.

Structured Early detection of Asymptomatic Liver Cirrhosis: Results of the population-based liver screening program SEAL.

Background & Aims: Detection of patients with early cirrhosis is of importance to prevent the occurrence of complications and improve prognosis. The SEAL program aimed at evaluating the usefulness of a structured screening procedure to detect cirrhosis as early as possible.

Methods: SEAL was a prospective cohort study with a control cohort from routine care data.

Frequency of outpatient care adverse events in an occupational mutual insurance company in Spain.

Background: Occupational mutual insurance companies (OMICs), in collaboration with the Spanish Social Security System, provide healthcare and manage the economic benefits for the workers in Spain. They have ambulatory care centers that attend outpatient trauma pathology, although most of the studies published have focused on surgical and hospital activity. The aim of this study was to detect adverse events (AEs) in outpatient trauma care in the context of an OMIC.

The response of zinc transporter gene expression of selected tissues in a pig model of subclinical zinc deficiency.

This study compared the relative mRNA expression of all mammal zinc (Zn) transporter genes in selected tissues of weaned piglets challenged with short-term subclinical Zn deficiency (SZD). The dietary model involved restrictive feeding (450 g/animal*day) of a high-phytate diet (9 g/kg) supplemented with varying amounts of zinc from ZnSO*7HO ranging from deficient to sufficient supply levels (total diet Zn: 28.1, 33.

In-Vitro Assessment of the Effects of Transcatheter Aortic Valve Leaflet Design on Neo-Sinus Geometry and Flow.

Transcatheter aortic valve (TAV) leaflet thrombosis is a clinical risk with potentially fatal consequences. Studies have identified neo-sinus flow stasis as a cause of leaflet thrombosis. Flow stasis is influenced by the TAV leaflets, which affect the local fluid dynamics in the aortic sinus and neo-sinus.

Simultaneous Analysis of Epoxidized and Hydroperoxidized Triacylglycerols in Canola Oil and Margarine by LC-MS.

The progress of lipid oxidation in foods is evaluated by measuring the peroxides and their scission products. However, hydrogen abstraction-independent pathways are not considered by commonly applied methods despite the known reactivity of epoxides toward biomolecules. Herein, a novel liquid chromatography tandem-mass spectrometry method was developed to detect hydroperoxidized and epoxidized triacylglycerols (TAGs) without derivatization or hydrolyzation of food samples.

Biomechanics of Endothelial Tubule Formation Differentially Modulated by Cerebral Cavernous Malformation Proteins.

At early stages of organismal development, endothelial cells self-organize into complex networks subsequently giving rise to mature blood vessels. The compromised collective behavior of endothelial cells leads to the development of a number of vascular diseases, many of which can be life-threatening. Cerebral cavernous malformation is an example of vascular diseases caused by abnormal development of blood vessels in the brain.

Risk Management in the Ambulatory Care Process in a Mutual Benefit Association Covering Work-Related Accidents and Diseases: Applying Modified Failure Mode and Effect Analysis (FMEA) Methodology.

Aim: To assess the impact of different forms of use of failure mode and effect analysis methodology for risk prioritization in the ambulatory care process in a mutual benefit association covering work-related accidents and diseases.

Methods: The study is based on a previously drafted and individually prioritized risk map by a multidisciplinary team made up of patient safety committee members from health care centers and clinics in a mutual benefit association covering work-related accidents and diseases. The professionals mainly carry out their work in the field of management (individual manager group (IMG)).

Quality Assurance and Patient Safety Measures: A Comparative Longitudinal Analysis.

Objective: To analyze whether the results on quality assurance and safety culture in a healthcare organization are related to and affected by the actions implemented.

Setting: Health Insurance of Work-related Accidents and Occupational Diseases.

Methods: The study was conducted as a longitudinal observational study that analyzed the relationship of the Safety Culture and Quality Assurance measurements.

Patient Safety Culture in Mutual Insurance Companies in Spain.

Objectives: The aim of the study was to assess the safety culture in a mutual insurance sector, searching for improvement opportunities. This sector offers health insurance for work-related injuries and occupational illnesses and represents an annual volume of patients corresponding to approximately 10% of the working population in Europe.

Methods: A cross-sectional study was conducted to assess the safety culture in the mutual insurance sector in Spain.

[Implementation of good quality and safety practices. Descriptive study in a occupational mutual health centre].

Objective: To describe the level of implementation of quality and safety good practice elements in a Mutual Society health centre.

Method: A Cross-sectional study was conducted to assess the level of implementation of good practices using a questionnaire. Some quality dimensions were also assessed (scale 0 to 10) by a set of 87 quality coordinators of health centres and a random sample of 54 healthcare professionals working in small centres.

Cis and trans selective 1,4-addition of a lithium dithioester enolate to 4-O-TBS-2-cyclohexenone.

The 1,4-addition of the lithium enolate of methyldithioacetate (LMDTA) to (+/-)-4-O-TBS-2-cyclohexenone (3) can be varied from being highly 3,4-trans selective to being highly 3,4-cis selective simply by varying the reaction temperature. This stereodivergency allows expedient syntheses of the corresponding trans and cis methyl esters 6t and 6c and derived bicyclic ketolactones 7t and 7c.

Noninvasive method for measuring local hemoglobin oxygen saturation in tissue using wide gap second derivative near-infrared spectroscopy.

A simple continuous wave near-infrared algorithm for estimating local hemoglobin oxygen saturation in tissue (%StO2) is described using single depth attenuation measurements at 680, 720, 760, and 800 nm. Second derivative spectroscopy was used to reduce light scattering effects, chromophores with constant absorption, baseline/instrumentation drift, and movement artifacts. Unlike previous second derivative methods which focused primarily on measuring deoxyhemoglobin concentration; a wide 40 nm wavelength gap used for calculating second derivative attenuation significantly improved sensitivity to oxyhemoglobin absorption.

PROPHIS: parabolic trough-facility for organic photochemical syntheses in sunlight.

The PROPHIS facility is an efficient tool for the synthesis of chemicals with moderately concentrated sunlight on a semi-technical scale. The feasibility of selected solar photochemical reaction classes--including heterogeneous and homogeneous reactions--has been demonstrated using various set-ups of the plant. This paper outlines the potential of solar photochemistry by representative examples.

Equation of states for classical Coulomb systems: use of the Hubbard-Schofield approach.

An effective method based on the Hubbard-Schofield approach [Phys. Lett. A 40, 245 (1972)] is developed to calculate the free energy of classical Coulomb systems.

Evolution of induced axial magnetization in a two-component magnetized plasma.

In this paper, the evolution of the induced axial magnetization due to the propagation of an electromagnetic (em) wave along the static background magnetic field in a two-component plasma has been investigated using the Block equation. The evolution process induces a strong magnetic anisotropy in the plasma medium, depending nonlinearly on the incident wave amplitude. This induced magnetic anisotropy can modify the dispersion relation of the incident em wave, which has been obtained in this paper.

Energy loss of a charged particle in a magnetized quantum plasma.

This paper investigates the stopping power of a weakly coupled magnetized plasma. The effect of the Larmor rotation of the heavy charged test particle is carefully analyzed. The dielectric formalism is employed to obtain a general expression for the stopping power.

Stopping power of strongly coupled electronic plasmas: sum rules and asymptotic forms.

The stopping power of coupled electronic plasmas is investigated. Within the dielectric formalism and employing the method of frequency moments for the dielectric function we obtain a general formula describing the linear stopping power of a coupled plasma. Analytical results for the low- and high-projectile-velocity asymptotic forms are obtained.

Transglycosylation reactions with a crude culture filtrate from Thermoascus aurantiacus.

Some characteristics of regioselectivity and acceptor tolerance in transglycosylation reactions, catalysed by a crude culture filtrate from Thermoascus aurantiacus, were examined by employing methanol and monosaccharides as acceptors. When beta-D-mannopyranosyl fluoride was employed as the donor, the anomeric configuration of the newly formed bond was found to depend on the structure of the acceptor used.

Simultaneous detection of different glycosidase activities by 19F NMR spectroscopy.

A fast method for the simultaneous detection of different glycosidolytic activities in commercially available enzyme preparations and crude culture filtrates was found in using, as substrate, a mixture of different glycosyl fluorides and 19F NMR spectroscopy as a screening technique. Accompanying studies regarding the hydrolytic stability of these fluorides in various buffer systems, as well as conditions of their long-term storage, were carried out. A simple procedure for the preparation of beta-D-mannopyranosyl fluoride in gram quantities is given.