Identification and measurement of intensive economic growth in a Roman imperial province.

A key question in economic history is the degree to which preindustrial economies could generate sustained increases in per capita productivity. Previous studies suggest that, in many preindustrial contexts, growth was primarily a consequence of agglomeration. Here, we examine evidence for three different socioeconomic rates that are available from the archaeological record for Roman Britain.

Effect of insulin resistance on CAC scores in cancer survivors.

Background: Many ca. survivors exhibit signs of IR, an important risk factor for the development of CAD. CAC scans offer a risk assessment of CV disease before cardiac damage has occurred.

Provisioning an Early City: Spatial Equilibrium in the Agricultural Economy at Angkor, Cambodia.

Unlabelled: A dominant view in economic anthropology is that farmers must overcome decreasing marginal returns in the process of intensification. However, it is difficult to reconcile this view with the emergence of urban systems, which require substantial increases in labor productivity to support a growing non-farming population. This quandary is starkly posed by the rise of Angkor (Cambodia, 9th-fourteenth centuries CE), one of the most extensive preindustrial cities yet documented through archaeology.

Palm springs on the Rio Grande: Insight into Archaic forager plant use from phytoliths recovered from a Late Holocene alluvial section in northern New Mexico.

In this study we present new evidence from phytolith studies for the presence of Sabal sp. (likely minor), an allochthonous plant, around Tesuque Creek in northern New Mexico during the early part of the Late Holocene, in the vicinity of known Late Archaic hunter-gatherer communities using the area at that time. We analyzed phytoliths from sediments taken from an alluvial section on the east side of Tesuque Creek dating to c.

Diachronic modeling of the population within the medieval Greater Angkor Region settlement complex.

Angkor is one of the world's largest premodern settlement complexes (9th to 15th centuries CE), but to date, no comprehensive demographic study has been completed, and key aspects of its population and demographic history remain unknown. Here, we combine lidar, archaeological excavation data, radiocarbon dates, and machine learning algorithms to create maps that model the development of the city and its population growth through time. We conclude that the Greater Angkor Region was home to approximately 700,000 to 900,000 inhabitants at its apogee in the 13th century CE.

Cities: Complexity, theory and history.

In recent decades researchers in a variety of disciplines have developed a new "urban science," the central goal of which is to build general theory regarding the social processes underlying urbanization. Much work in urban science is animated by the notion that cities are complex systems. What does it mean to make this claim? Here we adopt the view that complex systems entail both variation and structure, and that their properties vary with system size and with respect to where and how they are measured.

Smithian growth in a nonindustrial society.

A defining feature of the contemporary world is economic growth, and the most frequently cited cause is technological change, especially with respect to energy capture and information processing. This framing masks the potential for economic growth in nonindustrial societies, but there is growing evidence for episodes where the material conditions of life did improve in the preindustrial past. Here, we explore a potential mechanism behind these improvements.

Urbanism and the division of labour in the Roman Empire.

One of the hallmarks of human agglomeration is an increase in the division of labour, but the exact nature of this relationship has been debated among anthropologists, sociologists, economists, and historians and archaeologists. Over the last decade, researchers investigating contemporary urban systems have suggested a novel explanation for the links between the numbers of inhabitants in settlements and many of their most important characteristics, which is grounded in a view of settlements as social networks embedded in built environments. One of the remarkable aspects of this approach is that it is not based on the specific conditions of the modern world (such as capitalism or industrialization), which raises the issue of whether the relationships observed in contemporary urban systems can also be detected in pre-modern urban or even non-urban systems.

Prehistoric mitochondrial DNA of domesticate animals supports a 13th century exodus from the northern US southwest.

The 13th century Puebloan depopulation of the Four Corners region of the US Southwest is an iconic episode in world prehistory. Studies of its causes, as well as its consequences, have a bearing not only on archaeological method and theory, but also social responses to climate change, the sociology of social movements, and contemporary patterns of cultural diversity. Previous research has debated the demographic scale, destinations, and impacts of Four Corners migrants.

Bone Morphogenetic Protein 2 Alters Osteogenesis and Anti-Inflammatory Profiles of Mesenchymal Stem Cells Induced by Microtextured Titanium In Vitro.

Objectives: Microtextured titanium (Ti) induces osteoblast differentiation of mesenchymal stem cells (MSCs) in the absence of exogenous osteogenic factors; and high-energy surface modifications speed healing of microrough Ti implants. Bone morphogenetic protein 2 (BMP2) is used clinically to improve peri-implant bone formation and osseointegration but can cause inflammation and bone-related complications. In this study, we determined whether BMP2 alters human MSC differentiation, apoptosis, and inflammatory factor production when grown on Ti implants with different surface properties.

Population-Area Relationship for Medieval European Cities.

Medieval European urbanization presents a line of continuity between earlier cities and modern European urban systems. Yet, many of the spatial, political and economic features of medieval European cities were particular to the Middle Ages, and subsequently changed over the Early Modern Period and Industrial Revolution. There is a long tradition of demographic studies estimating the population sizes of medieval European cities, and comparative analyses of these data have shed much light on the long-term evolution of urban systems.

Uniform Probability Density Analysis and Population History in the Northern Rio Grande.

One of the basic challenges facing archaeology is translating surface evidence into population estimates with sufficient chronological resolution for demographic analysis. The problem is especially acute when one is working with sites inhabited across multiple chronological periods and the production curves for pottery types are uafnknown. In this paper I present a Bayesian statistical method which I call that is tailored to this situation.

From the primordial soup to self-driving cars: standards and their role in natural and technological innovation.

Standards are specifications to which the elements of a technology must conform. Here, we apply this notion to the biochemical 'technologies' of nature, where objects like DNA and proteins, as well as processes like the regulation of gene activity are highly standardized. We introduce the concept of standards with multiple examples, ranging from the ancient genetic material RNA, to Palaeolithic stone axes, and digital electronics, and we discuss common ways in which standards emerge in nature and technology.

Sequential Curettage, 5-Fluorouracil, and Photodynamic Therapy for Field Cancerization of the Scalp and Face in Solid Organ Transplant Recipients.

Background: Field cancerization with actinic keratoses and squamous cell carcinoma in situ (AK/SCCIS) represents a common therapeutic challenge in solid organ transplant recipients (SOTRs). These patients often show inadequate responses to methods traditionally used as monotherapy (e.g.

THE SOCIAL CONSEQUENCES OF CLIMATE CHANGE IN THE CENTRAL MESA VERDE REGION.

The consequences of climate change vary over space and time. Effective studies of human responses to climatically induced environmental change must therefore sample the environmental diversity experienced by specific societies. We reconstruct population histories from A.

Demographic and Social Dimensions of the Neolithic Revolution in Southwest Colorado.

Domesticated food production is widely acknowledged as a crucial innovation that led to significant transformations in human demography and social organization. Here, we address demographic and social dimensions of the Neolithic Revolution in the Mesa Verde region of Southwest Colorado. We first propose a new method of dating habitations to one of two phases of the Basketmaker III period (AD 600-725) using relative frequencies of vessel forms in pottery assemblages.

Settlement scaling and increasing returns in an ancient society.

A key property of modern cities is increasing returns to scale-the finding that many socioeconomic outputs increase more rapidly than their population size. Recent theoretical work proposes that this phenomenon is the result of general network effects typical of human social networks embedded in space and, thus, is not necessarily limited to modern settlements. We examine the extent to which increasing returns are apparent in archaeological settlement data from the pre-Hispanic Basin of Mexico.

A semiflexible 64-channel receive-only phased array for pediatric body MRI at 3T.

Purpose: To design, construct, and validate a semiflexible 64-channel receive-only phased array for pediatric body MRI at 3T.

Methods: A 64-channel receive-only phased array was developed and constructed. The designed flexible coil can easily conform to different patient sizes with nonoverlapping coil elements in the transverse plane.

DNA analysis of ancient dogs of the Americas: identifying possible founding haplotypes and reconstructing population histories.

As dogs have traveled with humans to every continent, they can potentially serve as an excellent proxy when studying human migration history. Past genetic studies into the origins of Native American dogs have used portions of the hypervariable region (HVR) of mitochondrial DNA (mtDNA) to indicate that prior to European contact the dogs of Native Americans originated in Eurasia. In this study, we summarize past DNA studies of both humans and dogs to discuss their population histories in the Americas.

The pre-history of urban scaling.

Cities are increasingly the fundamental socio-economic units of human societies worldwide, but we still lack a unified characterization of urbanization that captures the social processes realized by cities across time and space. This is especially important for understanding the role of cities in the history of human civilization and for determining whether studies of ancient cities are relevant for contemporary science and policy. As a step in this direction, we develop a theory of settlement scaling in archaeology, deriving the relationship between population and settled area from a consideration of the interplay between social and infrastructural networks.

Indurated vascular plaques on the legs of an 85-year-old woman.

This is a case of classic type Kaposi sarcoma occurring in an 85-year-old woman who presented with indurated vascular plaques on both legs below the knee that has been present for two years. A brief review of the literature on Kaposi sarcoma is included.

Effect of palliative care services on the aggressiveness of end-of-life care in the Veteran's Affairs cancer population.

Background: Cancer care near the end of life (EOL) has become more aggressive over the years. Palliative care services (PCS) may decrease this aggressive cancer care in terminally ill cancer patients. Our objective was to observe the aggressiveness of cancer care near the EOL among Veterans Affairs cancer patients before and after the institution of a PCS team.