Publications by authors named "Orsolya Oravecz"

Article Synopsis
  • Miscarriages are common, occurring in 50-70% of pregnancies, with 1-5% of women experiencing recurrent pregnancy loss (RPL), which is defined as having two or more miscarriages.
  • Current understanding of the causes and mechanisms behind RPL is lacking, making reliable diagnostic and preventive methods unavailable.
  • The study assessed three placental proteins and found that lower levels of free-β-hCG and PAPP-A, particularly between 9-13 weeks of pregnancy, could serve as effective biomarkers for identifying RPL, suggesting issues with placental function and development.
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Introduction: Galectins are master regulators of maternal immune responses and placentation in pregnancy. Galectin-13 (gal-13) and galectin-14 (gal-14) are expressed solely by the placenta and contribute to maternal-fetal immune tolerance by inducing the apoptosis of activated T lymphocytes and the polarization of neutrophils toward an immune-regulatory phenotype.Furthermore, their decreased placental expression is associated with pregnancy complications, such as preeclampsia and miscarriage.

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Article Synopsis
  • Proteoglycans are crucial for various physiological processes related to pregnancy, such as cell adhesion, growth, and blood vessel formation, but their exact roles in human reproduction are not fully understood.
  • This overview highlights syndecan-1 as a key proteoglycan involved in trophoblast development and its altered expression in pregnancy complications like pre-eclampsia and fetal growth restriction.
  • The findings suggest that proteoglycans, particularly syndecan-1, play significant roles in placental function and may serve as indicators for healthy pregnancies and potential complications, warranting further research for diagnostic and therapeutic applications.
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Wastewater based epidemiology is a potential early warning tool for the detection of COVID-19 outbreak. Sewage surveillance for SARS-CoV-2 RNA was introduced in Hungary after the successful containment of the first wave of the pandemic to forecast the resurge of infections. Three wastewater treatment plants servicing the entire population (1.

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Four actinomycete strains, isolated from the overheated region of manure compost, were assigned to the genus Thermobifida on the basis of morphological, physiological and biochemical characteristics. All strains produced single, ovoid, heat-sensitive spores on dichotomically branched aerial hyphae. On the basis of chemotaxonomic traits, these isolates showed strong affinity towards members of the genus Thermobifida.

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