Publications by authors named "Orrett F"

Trichomoniasis is the most common non-viral sexually transmitted disease (STD) globally and yet is not a reportable disease. is an important source of reproductive morbidity and may increase risk of acquisition and transmission of human immunodeficiency viruses (HIV). The World Health Organization (WHO) and the Control Disease Center (CDC) recommend various regimens of nitroimidazole s for treatment.

View Article and Find Full Text PDF

Background: (TV) is one of the most common pathogens causing sexually transmitted infections (STIs) in both men and women. Since there are no accurate prevalence data available on TV infection among women for Trinidad and Tobago and in the Caribbean region, there is a great need for research to study the dynamics of the infection and its transmission.

Objectives: To determine the prevalence and diagnose TV infection in women attending the STI clinic and to provide recommendations for control and prevention of trichomoniasis in the community.

View Article and Find Full Text PDF

Objectives: The objectives of this study were to determine the susceptibility of Methicillin Resistant Staphylococcus aureus (MRSA) isolates to Mupirocin and other antimicrobial agents and to record the prevalence and distribution of this organism at the University Hospital of the West Indies (UHWI).

Methods: MRSA isolates collected between January 1, 2008 and December 31, 2008, were tested for low and high level resistance to Mupirocin. Susceptibility testing to other antibiotics including cotrimoxazole, minocycline, tetracycline, clindamycin, erythromycin, gentamicin and vancomycin was also done.

View Article and Find Full Text PDF

The serogroup distribution and antimicrobial susceptibility patterns of Shigella isolates obtained from stool specimens of persons with acute diarrhoea in community-based studies from southern Trinidad during 1997-2006 were reviewed. Of the 5,187 stool specimens, 392 (8%) were positive for Shigella organisms. From these 392 isolates, 88.

View Article and Find Full Text PDF

The objective of the study was to investigate the trend of mupirocin resistance among methicillin-resistant Staphylococcus aureus (MRSA) in Trinidad. No premarketing susceptibility surveillance was ever done following the introduction of mupirocin in 1986. A total of 188 MRSA strains recovered over a 2-year period from various body sites were tested for mupirocin resistance via the disc diffusion method.

View Article and Find Full Text PDF

Urinary tract infection is a common condition worldwide; responsible for significant morbidity in both hospitalized and community patients. The laboratory records, for microbial isolates of infected urine and their susceptibility profiles for the years 1999 and 2003 were retrospectively reviewed and compared. In 2003, there was a significant decline in recovery ofCitrobacter spp compared to 1999.

View Article and Find Full Text PDF

Objective: The objective of this study was to provide a Trinidadian perspective on pediatric community-acquired and hospital-acquired bacteremia via the documentation of common etiologic agents, antimicrobial profiles of the isolated pathogens, and patient outcome.

Methods: This was a six-year retrospective study of children with bacteremia admitted to the pediatric wards of the San Fernando General Hospital, Trinidad.

Results: Seven hundred and four episodes of pediatric bacteremia were reviewed during the six-year study period.

View Article and Find Full Text PDF

Background: Methicillin-resistant Staphylococcus aureus (MRSA) has become one of the most widespread causes of nosocomial infections worldwide. Recently, reports have emerged that S. aureus strains recovered from community-acquired infections are also methicillin-resistant.

View Article and Find Full Text PDF

Objective: To assess the frequency of Klebsiella pneumoniae (K. pneumoniae) recovery from clinical specimens from hospital and community patients, their antibiotic profile, the extent of extended-spectrum beta lactamase (ESBL) production among such isolates, and the impact on patient management.

Methods: The study recovered 1,118 K.

View Article and Find Full Text PDF

Antimicrobial susceptibilities of 156 Streptococcus pneumoniae strains isolated from 1994 through 2002 were studied. Of this total, 38.7, 26.

View Article and Find Full Text PDF

A two-year prospective study of 554 Pseudomonas aeruginosa isolates was recovered from various clinical sources throughout Trinidad, and their resistance patterns to antipseudomonal antimicrobial agents were determined. Of the 554 P. aeruginosa isolates, 20.

View Article and Find Full Text PDF

Objective: To determine the prevalence of antimicrobial resistance among gram-negative aerobic bacteria isolated from infected patients on the intensive care unit (ICU) and the outcome of infected patients.

Methods: Over a 5-year period (January 1998 to December 2002), all gram-negative aerobic bacteria (GNB) consecutively isolated from infected ICU patients at General Hospital, San Fernando, Trinidad and Tobago, West Indies. were tested for susceptibility to 10 commonly prescribed antimicrobial agents.

View Article and Find Full Text PDF

The antibiotic prescribing patterns on 527 case notes of discharged patients over a two-month period at a teaching hospital in southern Trinidad were retrospectively analyzed. Forty four percent of patients had received one or more antibiotics. The greatest exposure rate was on the orthopedic (79.

View Article and Find Full Text PDF

Background: The present study took place at the antenatal clinics of the San Fernando General Hospital located in the south and the Mount Hope Maternity Hospital located in the north-west of the West Indies, respectively. Participants were from the lower socioeconomic group that included representatives from the two major ethnic groups, East Indians and people of African descent.

Methods: We prospectively analyzed data on 201 third trimester pregnant women.

View Article and Find Full Text PDF

The prevalence of antimicrobial resistance among urinary pathogens has been increasing worldwide. Laboratory diagnosed urinary tract infections were retrospectively evaluated for the years 1996 through 1999, to document the common pathogens and their changing antimicrobial profiles. From 14,853 hospital specimens, an isolation rate of 6.

View Article and Find Full Text PDF

The nosocomial infection rate in the intensive care unit (ICU) of a private hospital was assessed during an 18-month survey. From 629 admissions to the ICU, 139 hospital-acquired infections were identified. The rate was 22.

View Article and Find Full Text PDF

Objective: To investigate the prevalence of significant enterococcal isolates from urine and determine what factors are associated with the increased prevalence, with particular reference to antibiotic susceptibilities.

Methods: Retrospective analysis over an 8-year period of hospital laboratory records of urinary isolates of enterococci was done. Species were identified via colony morphology, growth in 6.

View Article and Find Full Text PDF

The purpose of the study was to determine the level of knowledge and attitudes among pre-university students in Trinidad and Tobago on the pre-disposing factors and prevention of tuberculosis and the management of persons with the disease. More than 90% (542 of 600) of participating students from nine secondary schools duly completed the self-administered questionnaires. Two-thirds of the students were girls (336) and the rest were boys (206).

View Article and Find Full Text PDF

Objective: To study the serotype distribution of non-typhoidal salmonella isolated from clinical specimens and to evaluate their susceptibility patterns to the most commonly prescribed antimicrobial agents used in this region.

Methods: A retrospective study during the period 1993 1999 was carried out at the Eric Williams Medical Sciences Complex Microbiology Laboratory, a teaching hospital in the northwestern part of Trinidad. Strains of non-typhoidal salmonella were serogrouped with polyvalent Salmonella O antiserum and sent to the local Public Health Laboratory for confirmation and further serotyping.

View Article and Find Full Text PDF

Among 1470 elderly hospitalized and nonhospitalized people, 566 cases of bacteriuria were identified. There were 663 men (41.5% with bacteriuria) and 807 women (36.

View Article and Find Full Text PDF

Antimicrobial susceptibility patterns of strains of Escherichia coli isolated between 1994 and 1998 were studied. Of the 1,283 strains examined, 75% were recovered from urine, 8.7% from wounds, 3.

View Article and Find Full Text PDF

Objective: A prospective study was carried out at a General Practice in South Trinidad, to assess the sensitivity profiles of urinary isolates in this remote rural community.

Methods: Quantitative bacteriologic cultures were performed according to standard procedures. Identification of isolates was based on gram reaction, morphology and biochemical reactions.

View Article and Find Full Text PDF

A total of 132 neonatal deaths among 627 infants admitted to the neonatal ward of the San Fernando General Hospital, Trinidad over a 2-year period were reviewed. The most common cause of death was prematurity (43.9%).

View Article and Find Full Text PDF