Nanomedicine formulations for respiratory infections by inhalation delivery: Covid-19 and beyond.

For respiratory infections treatment and prevention, we analyze for the first time the possibility of providing a broad range medication based on metallic nanoparticles colloids (NpC) delivery by controlled aerosol inhalation. (i) Based on in-vitro data combined with aerosol deposition characteristics in the respiratory system, we calculate the required effective formulations, dosages and delivery parameters for an aerosol inhalation treatment. The goal is to achieve an effective NpC inhibitory concentration (IC) in the target airway surface liquid (ASL); (ii) We evaluate the clinical safety of such dosages, drawing on information from animal testing data and regulatory limits in the USA for such nanoparticles aerosol inhalation safety.

Incipient order in the t-J model at high temperatures.

We analyze the high-temperature behavior of the susceptibilities towards a number of possible ordered states in the t-J-V model using the high-temperature series expansion. From all diagrams with up to ten edges, reliable results are obtained down to temperatures of order J, or (with some optimism) to J/2. In the unphysical regime, tJ, these susceptibilities are small and decreasing with decreasing temperature; this suggests that the t-J model does not support high-temperature superconductivity.

Dimensional crossover and charge order in half-doped manganites and cobaltites.

We propose a generic model for understanding the effect of quenched disorder on charge-ordering in half-doped manganese and cobalt oxides with different crystal structures. Current experimental observations are explained in the light of the global phase diagram of the model.