[CAN NATURAL SKIN CREASE PREDICT OUR PHALANX JOINT ALIGNMENT?].

Background: Proximal interphalangeal injury may result in malalignment of the phalanx axis of motion. In some instances, these fractures are treated with an external fixation method such as Suzuki-type fixation, during which the surgeon must perform X-rays to preserve the phalanx anatomical axis of motion.

Objectives: To assess the correlation between the palmar skin crease and the joint axis of the proximal interphalangeal joint (PIPJ) of the fingers opposing the thumb to improve the surgeons' perioperative planning procedure.

Patterns of osteoarthritis in long finger joints: an observational cadaveric study with potential biomechanical considerations.

Purpose: To explore the distribution and prevalence of osteoarthritis in metacarpophalangeal, proximal interphalangeal and distal interphalangeal joints in long fingers in a cadaveric study, and to discuss potential biomechanical influences on these patterns.

Methods: This cadaveric study evaluated 144 metacarpophalangeal, proximal interphalangeal and distal interphalangeal joints from 12 embalmed cadaver hands. A dorsal dissection approach was used to expose the joints, which were then marked with color-coded pegs for consistent orientation during imaging.

Factors Associated with Exclusive Breastfeeding at Hospital Discharge among Native-Born, Immigrant, and Refugee Women.

Background: Exclusive breastfeeding is recommended through six months as it supports infant growth and development. Yet, many mothers do not exclusively breastfeed in early postpartum.

Objectives: To examine factors associated with exclusive breastfeeding at hospital discharge among culturally diverse women.

Variational approach for Stokes flow through a two-dimensional non-uniform channel.

A variational approach is proposed to study the Stokes flow in a two-dimensional non-uniform channel. By using the stationarity of the Lagrangian, the Euler-Lagrange equations are established which leads to a simple set of ordinary differential equations to provide an estimate for the average pressure drop explicitly in terms of the channel shape function. The results for the pressure drop show an excellent agreement with the second-order extended lubrication theory.

Soft wetting: Substrate softness- and time-dependent droplet/bubble adhesion.

Hypothesis: The droplet/bubble adhesion characteristics depend on the length of the droplet/bubble three-phase contact line. Since the deformation caused by the liquid-gas interfacial tension on the soft substrate, referred as to the wetting ridge, retards contact line spreading and retraction, we conjecture that the droplet/bubble adhesion characteristics depend also on the substrate softness.

Experiments: Soft substrates with various shear moduli are prepared and characterized by the spreading and receding dynamics of water droplets and underwater bubbles.

Dynamic and Quasi-static Droplet Penetration through Meshes.

We investigate experimentally the effects of pore size, surface wettability, and penetration mode on the characteristics of liquid penetration through meshes. Utilizing the impact of droplets and the hydrostatic pressure, we study water penetration through superhydrophobic, hydrophobic, superhydrophilic, and hydrophilic meshes with different uniform radii and pitch values of the pores. In the case of dynamic penetration enabled by the droplet impact, our results show that surface wettability has a negligible effect on either the threshold speed of the droplet penetration or the penetrating liquid mass.

Effect of reduced two-dose (1+1) schedule of 10 and 13-valent pneumococcal conjugate vaccines (Synflorix and Prevenar13) on nasopharyngeal carriage and serotype-specific immune response in the first two years of life: Results from an open-labelled randomized controlled trial in Indian children.

Introduction: This study aimed to assess the effect of a reduced dose regime (1 + 1) of PCV10 and PCV13 along with 3-dose regimes on pneumococcal vaccine-type (VT) carriage and immunogenicity in the first two years of life in PCV-naïve Indian children.

Methods: A total of 805 healthy infants aged 6-8 weeks were randomised to 7 groups (n = 115). Six groups received Synflorix(PCV10) or Prevenar13(PCV13) in the following schedules: 3 + 0 (three primary at 6, 10, and 14 weeks); 2 + 1 (two primary 6 and 14 weeks with booster at 9 months; 1 + 1 (one primary at 14 weeks with booster at 9 months).

[RADIAL TUNNEL SYNDROME].

The radial tunnel syndrome (RTS) is an entrapment of the radial nerve in the forearm. It is characterized by pain focused on the trapping area in the proximal forearm as well as pain radiated down the forearm. The syndrome is more common in men and in our estimation, there is a circumstantial connection to the continuous use of the computer keyboard.

Trigger Finger Due to Anomaly of Lumbrical Insertion: A Case Report and Review of Literature.

Case: Trigger finger (TF), or stenosing synovitis, is a common condition that can usually be diagnosed by physical examination. We recently operated on a patient with TF who did not respond to conservative treatment. At surgery, we found an anomalous insertion of the fourth lumbrical muscle to the A1 pulley.

[DE QUERVAIN'S TENOSYNOVITIS - CLINICAL PRESENTATION AND TREATMENT].

De-Quervain tenosynovitis, named after the Swiss surgeon Fritz De Quervain, is a condition characterized by pain and tenderness over the first extensor compartment of the wrist. This compartment contains the extensor pollicis brevis (EPB) and abductor pollicis longus (APL) tendons in their individual retinacular sheath. Non-inflammatory thickening of the tendinous sheath leads to entrapment of the individual tendons and increased friction.

[MEDIAN NERVE COMPRESSION BY LIPOMA CAN MIMIC CARPAL TUNNEL SYNDROME].

Lipoma of the nerve is an uncommon tumor, and usually has the highest incidence in the upper limb, especially in the median nerve. When the lesion is large it can cause peripheral neuropathy such as carpal tunnel syndrome. Therefore, a physical examination is paramount for correct surgery and patient preparation.

Contribution of malaria and sickle cell disease to anaemia among children aged 6-59 months in Nigeria: a cross-sectional study using data from the 2018 Demographic and Health Survey.

Objectives: To estimate the fraction of anaemia attributable to malaria and sickle cell disease (SCD) among children aged 6-59 months in Nigeria.

Design: Cross-sectional analysis of data from Nigeria's 2018 Demographic and Health Survey (DHS).

Setting: Nigeria.

The Consortium on Newborn Screening in Africa for sickle cell disease: study rationale and methodology.

Sickle cell disease (SCD) is a common condition within sub-Saharan Africa and associated with high under-5 mortality (U5M). The American Society of Hematology instituted the Consortium on Newborn Screening in Africa (CONSA) for SCD, a 7-country network of sites to implement standardized newborn hemoglobinopathy screening and early intervention for children with SCD in sub-Saharan Africa. CONSA's overall hypothesis is that early infant SCD screening and entry into standardized, continuous care will reduce U5M compared with historical estimates in the region.

Potential Impacts of Mass Nutritional Supplementation on Measles Dynamics: A Simulation Study.

The bidirectional interaction between undernutrition and infection can be devastating to child health. Nutritional deficiencies impair immunity and increase susceptibility to infection. Simultaneously, infections compound undernutrition by increasing metabolic demand and impairing nutrient absorption.

[MEDIAL EPICONDYLITIS (GOLFER'S ELBOW) - CLINICAL PRESENTATION AND TREATMENT].

Medial epicondylitis, which is also called "Golfer's Elbow" is a pathology which typically presents as medial elbow pain. It affects 1% of the general population, yet affects 3.8% to 8.

[MULTIPLE GIANT CELL TUMOR OF TENDON SHEATH: A CASE REPORT OF THREE LESIONS ON THE SAME FLEXOR TENDON].

We present a case report of a triple location Giant Cell Tumor of tendon sheath appearance on the same flexor tendon sheath of a single digit. There have been scarce descriptions of multiple Giant Cell Tumors of tendon sheath. Multiple tumors may predispose patients to a higher recurrence rate; therefore, recognition and treatment of this rare entity is important.

[ACUTE INJURY TO FLEXOR TENDONS OF THE HAND: ASSESSMENT, DIAGNOSIS AND TREATMENT].

Hand lacerations are common injuries seen by the primary care physician. Even seemingly small cuts carry a high risk of injury to flexor tendons of the hand which requires surgical treatment by a specialist. Elucidation of the relevant history, along with a dedicated and focused physical examination is imperative for an early intervention which, along with a meticulous surgical technique and dedicated rehabilitation by occupational therapists, will lead to a much improved functional prognosis for the patient.

Understanding Research Methods: Up-and-down Designs for Dose-finding.

For the task of estimating a target benchmark dose such as the ED50 (the dose that would be effective for half the population), an adaptive dose-finding design is more effective than the standard approach of treating equal numbers of patients at a set of equally spaced doses. Up-and-down is the most popular family of dose-finding designs and is in common use in anesthesiology. Despite its widespread use, many aspects of up-and-down are not well known, implementation is often misguided, and standard, up-to-date reference material about the design is very limited.

Family-Assisted Severity of Illness Monitoring for Hospitalized Children in Low-Resource Settings-A Two-Arm Interventional Feasibility Study.

Introduction: Pediatric mortality remains unacceptably high in many low-resource settings, with inpatient deaths often associated with delayed recognition of clinical deterioration. The Family-Assisted Severe Febrile Illness ThERapy (FASTER) tool has been developed for caregivers to assist in monitoring their hospitalized children and alert clinicians. This study evaluates feasibility of implementation by caregivers and clinicians.

Effect of adolescent pregnancy on child mortality in 46 countries.

Introduction: Adolescent pregnancy is a known health risk to mother and child. Statements and reports of health outcomes typically group mothers under 20 years old together. Few studies examined this risk at a finer age resolution, none of them comprehensively, and with differing results.

The Gantzer transfer - Assessment of the feasibility of using the nerve supplying the Gantzer muscle for end-to-side supercharging of the ulnar nerve.

Our study aimed at assessing the anatomical feasibility of using the nerve supplying the Gantzer muscle (GM) to supercharge the ulnar nerve following injury. The GM nerve was dissected and measured in 36 forearms. The distance between its origin and the lateral epicondyle of humerus and between the GM nerve and the ulnar nerve was measured.

Neglected congenital trigger thumb.

We present a case of neglected trigger thumb in a forty-year-old male. The patient presented to our clinic due to bilateral triggering of his fourth digit. He attested to having pain and limitation of joint movement of his left thumb since his childhood in the former Soviet Union, with occasional triggering.