Publications by authors named "Ornthipa Sethabutr"
Article Synopsis
- Shigellosis is a significant public health issue in China, particularly affecting children under 5, and traditional culture methods may underestimate its prevalence.
- Real-time PCR was used in this study to detect Shigella infections alongside routine culture, revealing a higher true burden of disease.
- The study found that 58% of culture-negative specimens were positive for Shigella DNA, indicating that conventional methods may overlook many cases, highlighting the need for improved detection techniques.
Article Synopsis
- Shigellosis, a diarrheal disease causing over 1,000,000 deaths globally each year, poses a significant burden in low-resource Asian countries, and this study aims to provide updated data on the disease.
- The study analyzed over 600,000 people across Bangladesh, China, Pakistan, Indonesia, Vietnam, and Thailand, revealing a 5% incidence of Shigella in diarrhea cases, with higher rates in young children and adults over 40.
- Findings indicate that S. flexneri is the most common Shigella species, with widespread antibiotic resistance, highlighting the need for prevention strategies to reduce overall diarrhea cases and improve public health in these regions.
