Publications by authors named "Orli Silverberg"

Laparoscopy is frequently used for the minimally invasive treatment of various gynaecological pathologies. Compared with laparotomy, laparoscopy is associated with faster recovery, better incision cosmesis, shorter hospital stays and lower postoperative pain and complications. Vulvar and/or labial oedema is an exceptionally rare postoperative complication of laparoscopy, and in this context, we present the case of a patient who developed unilateral vulvar oedema several hours after an uncomplicated laparoscopic ovarian cystectomy.

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The 2014 Update of the Canadian treatment recommendations for the management of spondyloarthritis recommended that patients at risk of peripheral spondyloarthritis, including patients with psoriatic arthritis (PsA), be assessed by a rheumatologist within 6 weeks of referral. This study aimed to: (1) investigate the proportion of PsA patients who were assessed by a rheumatologist within 6 weeks of referral to the PsA Clinic at Toronto Western Hospital and (2) investigate the possible reasons for delays for consult with a rheumatologist. We identified patients with PsA who were seen by rheumatologists at the PsA Clinic between January 2013 and May 2019.

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Article Synopsis
  • Liquid silicone is an affordable injectable option for soft tissue enhancement, but it carries a risk of delayed granuloma formation linked to high levels of tumor necrosis factor-α.
  • A case was reported involving persistent silicone granulomas after facial injections, which were successfully treated using tumor necrosis factor-α blockade.
  • Both this case and prior studies suggest that this treatment is effective for managing foreign body granulomas caused by silicone.
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Objective: To assess the correlation between cannabis use and psoriatic disease severity, health-related quality of life, pain, psychosocial outcomes, and cytokine levels in psoriasis (PsC) and psoriatic arthritis (PsA) patients.

Methods: PsC and PsA patients enrolled in the International Psoriasis and Arthritis Research Team (IPART) program were surveyed on cannabis use and were asked to provide a serum and urine sample. Demographic and clinical variables were compared between users and non-users using Student's t-test or Mann-Whitney U test for continuous variables, and chi-square or Fisher's exact test for categorical variables.

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Article Synopsis
  • * A literature search revealed that younger individuals, men, those with severe HS, and patients using specific medications like infliximab or adalimumab may be at increased risk for developing inflammatory arthritis.
  • * The findings highlight the importance of collaboration between rheumatology and dermatology to better manage the health of HS patients, given their higher likelihood of experiencing inflammatory arthritis.
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Background: Degos disease is a rare vascular disorder with a cutaneous-limited form, benign atrophic papulosis (BAP), and a systemic variant, malignant atrophic papulosis (MAP). Despite the poor prognosis of MAP, no study has established features associated with systemic disease.

Objectives: The aims of this systematic review were to: (1) summarize clinical features and treatments implemented for patients with MAP and BAP (2) identify clinical and laboratory factors associated with the development of MAP, compared to BAP.

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Background: Crohn's disease (CD) is a chronic, relapsing and remitting disease of the gastrointestinal tract that can cause significant morbidity and disability. Current treatment guidelines recommend early intervention with immunosuppressant or biological therapy in high-risk patients with a severe disease phenotype at presentation. The feasibility of therapeutic de-escalation once remission is achieved is a commonly encountered question in clinical practice, driven by patient and clinician concerns regarding safety, adverse events, cost and national regulations.

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Importance: Women with an infant with preterm birth (PTB) or who was severely small for gestational age (SGA) are at higher future risk of premature cardiovascular disease and related death.

Objective: To determine the risk of cardiac disease or death among women with an infant with both PTB and SGA.

Design, Setting, And Participants: This population-based cohort study used electronic health records from the province of Ontario, Canada, where health care is universally available, between April 1, 2002, and March 31, 2016.

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